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Late Side Effects After Image Guided Intensity Modulated Radiation Therapy Compared to 3D-Conformal Radiation Therapy for Prostate Cancer: Results From.

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Presentation on theme: "Late Side Effects After Image Guided Intensity Modulated Radiation Therapy Compared to 3D-Conformal Radiation Therapy for Prostate Cancer: Results From."— Presentation transcript:

1 Late Side Effects After Image Guided Intensity Modulated Radiation Therapy Compared to 3D-Conformal Radiation Therapy for Prostate Cancer: Results From 2 Prospective Cohorts  Ruud C. Wortel, MD, Luca Incrocci, MD, PhD, Floris J. Pos, MD, PhD, Uulke A. van der Heide, PhD, Joos V. Lebesque, MD, PhD, Shafak Aluwini, MD, Marnix G. Witte, PhD, Wilma D. Heemsbergen, PhD  International Journal of Radiation Oncology • Biology • Physics  Volume 95, Issue 2, Pages (June 2016) DOI: /j.ijrobp Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Fig. 1 (Top panel) Average dose to anorectum (A), anus (B), and bladder (C) as a function of SV dose. (Bottom panel) Relative anorectum surface (D), anus surface (E), and absolute bladder surface (F) receiving high dose above 60 Gy. Error bars represent 95% confidence intervals. Abbreviations: 3D-CRT = 3-dimensional conformal radiation; IG-IMRT = image guided intensity modulated radiation therapy; SV = seminal vesicle. International Journal of Radiation Oncology • Biology • Physics  , DOI: ( /j.ijrobp ) Copyright © 2016 Elsevier Inc. Terms and Conditions

3 Fig. 2 Kaplan-Meier curves of (A) overall gastrointestinal toxicity grade ≥2, (B) high stool frequency ≥6/day, (C) proctitis requiring corticosteroids, and (D) overall genitourinary toxicity grade ≥2. Abbreviations: 3D-CRT = 3-dimensional conformal radiation; IG-IMRT = image guided intensity modulated radiation therapy. International Journal of Radiation Oncology • Biology • Physics  , DOI: ( /j.ijrobp ) Copyright © 2016 Elsevier Inc. Terms and Conditions

4 Fig. 3 (A-H) Prevalence of patient-reported gastrointestinal and genitourinary symptoms. Error bars represent 95% confidence intervals. Statistically significant differences between IG-IMRT and 3D-CRT are *P<.05 or **P<.01. Abbreviations: 3D-CRT = 3-dimensional conformal radiation; IG-IMRT = image guided intensity modulated radiation therapy. International Journal of Radiation Oncology • Biology • Physics  , DOI: ( /j.ijrobp ) Copyright © 2016 Elsevier Inc. Terms and Conditions

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