1. Purposeful rotation of outer guide catheter just prior to embryo transfer: Does it enhance the pregnancy rate in women undergoing assisted reproduction ?  
aIVF & Reproductive Biology Centre, Department of Obstetrics and Gynecology, Maulana Azad Medical College, 2- Bahadur Shah Zafar Marg, New Delhi,
bVMMC and Safdarjung Hospital, New Delhi
cInstitute of Cytology and Preventive Oncology(ICMR) Sector -39, NOIDA, Uttara Pradesh
Aswathy Kumaran a, Sudha Prasad a, Saumya Prasad b, Supriya Hajela a, Shashi Sharma c and Yogesh Kumar a

2. Background….
Bringing to light a new variation in embryo tranfer technique associated with positive outcome…
Further systematic and prospective research needed…..

3. Study Objective STUDY OUTCOME
To assess the role of rotation of outer guide of embryo transfer catheter purposely to enhance pregnancy rate in women underwent IVF-ET cycles
STUDY OUTCOME
Clinical pregnancy rates

4. Study Design Retrospective Case control study
August 2014 to September year
All women who underwent embryo transfer at IVF & Reproductive Biology Centre, Maulana Azad Medical College, New Delhi
N=243

5. Group- B:Control group
Methodology
Total ETs 1 year
N=243
Group-A:Study
Intentional rotation of outer guide catheter just prior to embryo transfer step was performed
N=131
Group- B:Control group
Non rotation group
N=112

6. Methodology
Both groups were compared and evaluated for demographic profile, and other cycle characteristics
Student T-test, Mann Whitney U-test and Chi-Squares test were applied as appropriate and statistical significance was calculated at p<0.05

7. Results
No significant difference was found between group-A and group-B respectively in
between mean age (31.79±4.4 vs ±4.8 p=0.79**)
duration of infertility (8.9±4.4. vs. 8.6±4.9; p=0.81**)

8. Results
No significant difference was found between group-A and group-B respectively in
type of infertility and other cycle characteristics like hormonal profile endometrial thickness
number of oocytes retrieved

9. Results
No significant difference was found between group-A and group-B respectively in
fertilization rate and
grading of embryo(s)

10. The groups..matched Demographic parameters Group A (study)
Group B (control)
Age profile
31.79±4.4
32.21±4.8
Infertility duration
8.9±4.4.
8.6±4.9
Oocyte retrieval rate
10.8±4.4.
9.9±4.9
Fertilization rate
7.9 ±4.4.
7.1±4.9
No of embryos transferred
2.5±0.9
8.1±4.9
Embryo quality 8

11. Results
In Group A, The clinical pregnancy rates –
41.2% (54/131)
In Group B, the clinical pregnancy rates –
33% (37/112)
(p=0.001**)

12. Conclusion
The purposeful rotation was seen to be a positive factor involved responsible for successful pregnancy outcome

13. Implantation is a complex process involving ovarian steroids, a multitude of paracrine and autocrine factors, and interaction between multiple cell types. The mechanisms of implantation are not precisely known.

14. Thank you