1. International Neurourology Journal 2011;15:176-178
Atrophy of the Tongue as the Presenting Feature of Metastatic Prostate Cancer
Zreik Abdullah, Maitrey Darrad, Sanjeev Pathak
Department of Urology, Doncaster Royal Infirmary, Doncaster, United Kingdom
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (
org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

2. International Neurourology Journal 2011;15:176-178
Prostate cancer is the most frequently diagnosed solid organ cancer in men and is the second leading cause of cancer-related deaths in men in the United Kingdom.
Commonly, it metastasizes to bones and lymph nodes, however, in advanced hormone-refractory disease it may involve the skull base leading to associated cranial nerve palsies.
Cranial nerve palsy as the presenting feature of advanced hormone-sensitive prostate cancer is extremely rare.
To the best of our knowledge, we report the first case of solitary hypoglossal nerve palsy as the presenting feature of advanced prostate cancer.
Neurologists, neurosurgeons and otolaryngologists may be the first clinicians to see such a patient; therefore, prostate cancer should be amongst the differential diagnoses considered in middle-aged and elderly men presenting with a cranial neuropathy and evidence of skull metastasis.

3. International Neurourology Journal 2011;15:176-178
Fig. 1

4. International Neurourology Journal 2011;15:176-178
Fig. 2

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Figure Legends
Fig. 1. Patient with a right sided hypoglossal nerve palsy.
Fig. 2. Magnetic resonance imaging shows an abnormality of the right petrous bone and hypoglossal nerve.