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October 20, 2016 Farrokh Alemi, PhD.

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1 October 20, 2016 Farrokh Alemi, PhD.
Identifying Sequence October 20, 2016 Farrokh Alemi, PhD.

2 Every Multivariate Analysis Makes Sequence Assumptions

3 Covariates Are Measured at Baseline

4 Treatment is after Baseline

5 Outcomes Are Last

6 Sequence of Cross-Sectional Study
Covariates Treatment Outcome

7 Sequence of Diagnoses in a Cross-Sectional Study

8 Longitudinal Studies Indicate Timing

9 Different Variables for Same Event before or after Treatment

10 Definition of Variable Can Indicate Sequence
Demographics Medical History

11 Sequence Can Be Discovered, But Is Often Ignored

12 Many Algorithms Same Conclusions

13 Install Package install.packages("bnlearn") library(bnlearn)

14 Read Data, Remove Unwanted Variables
d=read.csv("simulatedbundleddata.csv") d=d[,-1] for(i in 1:ncol(d)){ d[,i]=as.factor(d[,i]) }

15 Download & Paste Blacklist Function
Time 1 Time 2 Black list

16 Now Test Different Algorithms Same Answer
##For grow-shrink use l=gssequence(d) ##For incremental association use l=iambsequence(d) ##For semi-interleaved HITON use l=hitonsequence(d)

17 Sequence Is Fundamental


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