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Illustration of the origin of tubular cysts

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1 Illustration of the origin of tubular cysts
Illustration of the origin of tubular cysts. A, Cartoon of a normal nephron showing the glomerulus and its tubule. B, Microdissection studies of early ADPKD kidneys show that cysts begin as small focal outgrowths from any nephron segment.186 As shown in this cartoon, more than one cyst can arise from a single nephron. (Modified from Watnick and Germino.201 Used with permission.) Source: Autosomal Dominant Polycystic Kidney Disease, The Online Metabolic and Molecular Bases of Inherited Disease Citation: Valle D, Beaudet AL, Vogelstein B, Kinzler KW, Antonarakis SE, Ballabio A, Gibson K, Mitchell G. The Online Metabolic and Molecular Bases of Inherited Disease; 2014 Available at: Accessed: October 16, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved

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