1. Bharathi Hattiangady 1 ;Ramkumar Kuruba 1 ;Ashok K. Shetty;
Acute Seizures in Old Age Leads to a Greater Loss of CA1 Pyramidal Neurons, an Increased Propensity for Developing Chronic TLE and Severe Cognitive Dysfunction
Bharathi Hattiangady 1 ;Ramkumar Kuruba 1 ;Ashok K. Shetty;
Medical Research and Surgery Services, Veterans Affairs Medical Center, Durham, NC Division of Neurosurgery, Department of Surgery, Duke University Medical Center, Durham, NC ;
Figure 5 Comparison of the frequency and intensity of spontaneous recurrent seizures SRS between the young adult rats and aged rats in the 2 nd and 3 rd months after three hours of acute seizure AS activity. Figures A1 & B1 compare the frequencies of all SRS A1 and the stage V seizures B1; the most severe form of SRS between the two age groups. Note that in aged rats that underwent three hours of AS activity, the overall frequency of SRS is 6.4 folds greater p 0.05 and the frequency of stage V seizures is 12.6 folds greater p 0.01, in comparison to young adult rats that underwent three hours of AS activity. However, the duration of individual SRS between the two age groups was comparable C1.
null,null,2(1),1-18. Doi:null