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Treatment of Cachexia With Ghrelin in Patients With COPD

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Presentation on theme: "Treatment of Cachexia With Ghrelin in Patients With COPD"— Presentation transcript:

1 Treatment of Cachexia With Ghrelin in Patients With COPD
Nagaya Noritoshi , MD, Itoh Takefumi , MD, Murakami Shinsuke , MD, Oya Hideo , MD, Uematsu Masaaki , MD, Miyatake Kunio , MD, Kangawa Kenji , PhD  CHEST  Volume 128, Issue 3, Pages (September 2005) DOI: /chest Copyright © 2005 The American College of Chest Physicians Terms and Conditions

2 Figure 1 Changes in serum GH level after a single administration of ghrelin in patients with COPD. CHEST  , DOI: ( /chest ) Copyright © 2005 The American College of Chest Physicians Terms and Conditions

3 Figure 2 Effects of a 3-week administration of ghrelin on food intake (left, A), body weight (middle, B), and lean body mass (right, C). CHEST  , DOI: ( /chest ) Copyright © 2005 The American College of Chest Physicians Terms and Conditions

4 Figure 3 Changes in hand-grip strength (left, A), maximal inspiratory pressure (middle, B), and maximal expiratory pressure (right, C) before and after ghrelin therapy. CHEST  , DOI: ( /chest ) Copyright © 2005 The American College of Chest Physicians Terms and Conditions

5 Figure 4 Changes in Karnofsky performance status score (left, A) and the distance walked in 6 min (right, B) before and after ghrelin therapy. CHEST  , DOI: ( /chest ) Copyright © 2005 The American College of Chest Physicians Terms and Conditions

6 Figure 5 Plasma norepinephrine level before and after ghrelin therapy.
CHEST  , DOI: ( /chest ) Copyright © 2005 The American College of Chest Physicians Terms and Conditions


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