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The Efficacy and Safety of Testosterone Undecanoate (Nebido®) in Testosterone Deficiency Syndrome in Korean: A Multicenter Prospective Study  Du Geon.

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Presentation on theme: "The Efficacy and Safety of Testosterone Undecanoate (Nebido®) in Testosterone Deficiency Syndrome in Korean: A Multicenter Prospective Study  Du Geon."— Presentation transcript:

1 The Efficacy and Safety of Testosterone Undecanoate (Nebido®) in Testosterone Deficiency Syndrome in Korean: A Multicenter Prospective Study  Du Geon Moon, MD, PhD, Min Gu Park, MD, PhD, Sung Won Lee, MD, PhD, Kwangsung Park, MD, PhD, Jong Kwan Park, MD, PhD, Sae Woong Kim, MD, PhD, Nam Cheol Park, MD, PhD, Tai Young Ahn, MD, PhD, Jae Seung Paick, MD, PhD, Ju Tae Seo, MD, PhD, Dae Yul Yang, MD, PhD, June Young Lee, PhD, Je Jong Kim, MD, PhD  The Journal of Sexual Medicine  Volume 7, Issue 6, Pages (June 2010) DOI: /j x Copyright © 2010 International Society for Sexual Medicine Terms and Conditions

2 Figure 1 Schedule of testosterone undecanoate injection and assessment of efficacy and safety. IIEF=International Index of Erectile Function; AMS=Aging Males' Symptoms; PSA=prostate-specific antigen; BMI=body mass index; GEQ=Global Efficacy Question. The Journal of Sexual Medicine 2010 7, DOI: ( /j x) Copyright © 2010 International Society for Sexual Medicine Terms and Conditions

3 Figure 2 According to initial fasting glucose level, patients were divided into two groups (Group I, N=41: glucose level ≥110mg/dL, Group II, N=72: glucose level<110mg/dL); in a comparison of the degree of decrease after treatment between groups I and II, glucose level of group I decreased more than that of group II, with statistical significance. (paired t-test, independent t-test). The Journal of Sexual Medicine 2010 7, DOI: ( /j x) Copyright © 2010 International Society for Sexual Medicine Terms and Conditions

4 Figure 3 Change of erectile function domain after treatment; 96 patients (testosterone replacement therapy only) did not use PDE5i with testosterone replacement therapy, whereas 17 patients (testosterone+vardenafil 20mg) used concomitant PDE5i from week 18 to the end of the study. Baseline scores and post-treatment scores for the erectile function domain of both groups showed no significant difference (independent t-test). IIEF=International Index of Erectile Function; PDE5i=phosphodiesterase type 5 inhibitor. The Journal of Sexual Medicine 2010 7, DOI: ( /j x) Copyright © 2010 International Society for Sexual Medicine Terms and Conditions

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