1. Chapter 19 Lytic vs. Lysogenic
What are the main differences between the two cycles
Know phage lambda cycles
What is a prophage?
How is prophage propagated?
What could trigger virus to depart from lysogenic cycle?
Difference between prophage and provirus
Virus Anatomy
Capsid and capsomeres
Nucleic acid
Membranous envelope
Where does this envelope come from?
What is the envelope made of?
Glycoprotiens – virus
Receptors – host cell
Proteins in the virus (e.g. reverse transcriptase, polymerase)
General/Classification
Obligate intracellular parasites
DNA or RNA genome, Single or double stranded
Protein coat and nucleic acid structural components
Some have envelopes – these usually infect what organisms?
What does the “host range” refer to?
Two characteristics used to classify a virus
Viruses
HIV - Retrovirus
Why is HIV retro (what does this mean?)
Mode of entry to host cell
Host range
Be familiar with replication cycle
Why is HIV so difficult to treat?
Prions
What is a prion?
What difficulties do we face in trying to treat prion diseases?