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The Risk of Bias and Sample Size of Trials of Spinal Manipulative Therapy for Low Back and Neck Pain: Analysis and Recommendations  Sidney M. Rubinstein,

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Presentation on theme: "The Risk of Bias and Sample Size of Trials of Spinal Manipulative Therapy for Low Back and Neck Pain: Analysis and Recommendations  Sidney M. Rubinstein,"— Presentation transcript:

1 The Risk of Bias and Sample Size of Trials of Spinal Manipulative Therapy for Low Back and Neck Pain: Analysis and Recommendations  Sidney M. Rubinstein, DC, PhD, Rik van Eekelen, BSc, Teddy Oosterhuis, MSc, Michiel R. de Boer, PhD, Raymond W.J.G. Ostelo, PhD, Maurits W. van Tulder, PhD  Journal of Manipulative & Physiological Therapeutics  Volume 37, Issue 8, Pages (October 2014) DOI: /j.jmpt Copyright © 2014 National University of Health Sciences Terms and Conditions

2 Fig 1 Detailed flowchart illustrating the trial search and selection of studies. RCT, randomized controlled trial; SMT, spinal manipulative therapy. Journal of Manipulative & Physiological Therapeutics  , DOI: ( /j.jmpt ) Copyright © 2014 National University of Health Sciences Terms and Conditions

3 Fig 2 Number of RCTs that have examined the effects of spinal manipulative therapy for neck and low back pain, presented in the used time epochs of approximately 5 years. Note: The epochs refer to the year of publication and the years of the first and last epoch have been modified due to the size of the epochs. Journal of Manipulative & Physiological Therapeutics  , DOI: ( /j.jmpt ) Copyright © 2014 National University of Health Sciences Terms and Conditions

4 Fig 3 Proportion of RCTs on spinal manipulative therapy for neck and low back pain, which fulfilled each of the risk of bias criteria (and thus have a low risk of bias), divided into the following: selection bias (a), performance bias (b), attrition bias(c), detection bias (d), and selective reporting bias (e). RCT, randomized controlled trial. Journal of Manipulative & Physiological Therapeutics  , DOI: ( /j.jmpt ) Copyright © 2014 National University of Health Sciences Terms and Conditions

5 Fig 4 Proportion of RCTs on spinal manipulative therapy for neck and low back pain where each risk of bias criterion was rated unclear, divided into the following: selection bias (a), performance bias (b), attrition bias (c), detection bias (d), and selective reporting bias (e). RCT, randomized controlled trial. Journal of Manipulative & Physiological Therapeutics  , DOI: ( /j.jmpt ) Copyright © 2014 National University of Health Sciences Terms and Conditions

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