1. Liver transplantation
Liceo Scientifico Francesco Redi
Liver transplantation
Teacher : Elisa Vannuccini
Student : Clara Matteini

2. The history of transplantations
Alexis Carrel
devised a
technique
for joining
two blood
vessels
Peter Medawar
demonstrated that incompatibility has genetic origin
Prof. Murray’s equipe did the first kidney transplantation
Prof. Starzl did the first liver transplantation
Second world war
1902
1954
1963

3. Main causes Cirrhosis Liver Cancer Hereditary diseases Hepatitis
Diseases of the bile ducts
Alchol abuse
Liver Cancer
Hereditary diseases

4. Three steps: Hepatectomy 2. Union of the anastomis
3. Devascularization of the ‘new’ liver

5. Where the ‘new’ liver comes from ?
Liver used for the transplantantion can be obtained from :
A person that died from lethal brain injuries
A living donor who donates part of his liver ( A high
compatibility is necessary – Generally a family member).
Transplantion of stamcells ( under experimentation )

6. Split liver
The liver of the donor can be divided in two parts and used for two receivers , usually the right part is given to an adult and the left part is given to a child.

7. Liver Transplant Risks
Reject
Bleeding
-Hyperacute
Infections
Failure
-Acute
-Chronic

8. Thanks for the attention !!!