1. Blood

2. FIGURE 11.2
All formed elements originate in the red bone marrow from an undifferentiated cell called a stem cell. Stem cells divide and differentiate, giving rise to the various types of blood cells.

3. Formed Elements

4. Erythrocytes (RBC) Biconcave/No Nucleus

5. Platelets/Thrombocytes

6. White Blood Cells: Granulocytes
Neutrophil

7. Granulocytes
Eosinophil

8. Granulocytes
Basophil

9. Agranulocytes
Lymphocyte

10. Agranulocytes
Monocyte
Give rise to macrophage

11. leukemia

12. Sickle Cell Anemia

13. Blood Types Blood types
genetically determined by the glycoproteins (antigens) found on the surface of RBCs
Determined by A, B antigens
Protein or polypeptide capable of inducing a specific immune response
Blood type is determined by the type of antigen located on the surface of the RBC.

14. FIGURE 11.7bc
Blood is typed by mixing it with serum known to contain antibodies specific for a certain antigen. If blood containing that antigen is mixed with the serum, the blood will agglutinate (clump). Thus, one drop of blood is mixed with serum containing anti-A and another drop with serum containing anti-B. A third drop of blood is mixed with serum containing antibodies to Rh. Agglutination in response to an antibody reveals the presence of the antigen.