1. Coconut Oil and Improvement in Alzheimer’s Disease
Rachel Lowry
Organiclifestylemagazine.com

2. Overview
Background
Study 1
Study 2
Conclusion

3. Coconut Oil Sat. fat = 92% MCTs=67-70%
Medium Chain Triglycerides (MCTs)
Ketones
Population health

4. Alzheimer’s 5.4 million Americans (2012)
Gradual accumulation of amyloid-β(Aβ) and intracellular neurofibrillary tangles.
17-20 years before disease is noticed
Diet could play important role

5. Coconut Oil + Alzheimer’s
(Extra) Virgin Coconut Oil
Do not re-heat
Glucose utilization is impaired in AD
Ketones can replace glucose as brain’s energy source

6. Study 1 Prevention of amyloid-βbuild-up in brain T2DM and CVD
Ketones can cross the blood-brain barrier easily
Caprylic acid and lauric acid

7. Caprylic & Lauric Acids

8. Study 2: The Newports
Dr. Newport claims she cured husband of AD with coconut oil
Many factors such as exercise, healthy diet, and many other supplements.

9. Study 2, cont’d Axona ® is FDA approved (2009)
Reger et al. (2004) found β-hydroxybutyrate most helpful
Krikorian (2012) found improvement in MCI subjects with a ketogenic diet

10. Conclusion
Though coconut oil is a saturated fatty acid, it does not show the negative side effects of other SFAs.
Axona ® and anticholinesterase medications
Do not reheat coconut oil
Not for T2DM or liver
problems
Need more research!!!

11. References
Fernando, W. M. A. D. B., Martin, I. J., Goozee, K. G., Brennan, C. S., Jayasena, V., Martins, R. N. (2015). The role of dietary coconut for the prevention and treatment of Alzheimer’s disease: Potential mechanisms of action. British Journal of Nutrition 114, doi: /S
Doty, L. (2012). Coconut oil for Alzheimer’s disease? Clinical Practice 1(2), doi: /j.cp
Reger, M. A., Henderson, S.T., Hale, C., Cholerton, B., Baker, L.D., Watson ,G.S., et al. (2004). Effects of beta-hydroxybutyrate on cognition in memory-impaired adults. Neurobiological Aging 25(3),
Krikorian, R., Shidler, M.D., Dangelo, K., Couch, S.C., Benoit, S.C., Clegg. D.J. (2012) Dietary ketosis enhances memory in mild cognitive impairment. Neurobiological Aging 33(2) 425.e19-27.