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Usefulness of Preprocedure High-Sensitivity C-Reactive Protein to Predict Death, Recurrent Myocardial Infarction, and Stent Thrombosis According to Stent.

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Presentation on theme: "Usefulness of Preprocedure High-Sensitivity C-Reactive Protein to Predict Death, Recurrent Myocardial Infarction, and Stent Thrombosis According to Stent."— Presentation transcript:

1 Usefulness of Preprocedure High-Sensitivity C-Reactive Protein to Predict Death, Recurrent Myocardial Infarction, and Stent Thrombosis According to Stent Type in Patients With ST-Segment Elevation Myocardial Infarction Randomized to Bare Metal or Drug-Eluting Stenting During Primary Percutaneous Coronary Intervention  Mikkel Malby Schoos, MD, Henning Kelbæk, MD, DMSc, Klaus F. Kofoed, MD, DMSc, PhD, Lars Køber, MD, DMSc, Lene Kløvgaard, RN, Steffen Helqvist, MD, DMSc, Thomas Engstrøm, MD, DMSc, PhD, Kari Saunamäki, MD, DMSc, Erik Jørgensen, MD, DMSc, Lene Holmvang, MD, DMSc, Peter Clemmensen, MD, DMSc  American Journal of Cardiology  Volume 107, Issue 11, Pages (June 2011) DOI: /j.amjcard Copyright © 2011 Elsevier Inc. Terms and Conditions

2 Figure 1 Adverse events by median high-sensitivity C-reactive protein level ≤2 mg/L (blue bars) and >2 mg/L (red bars). re-MI IRA = recurrent infarction in infarct-related artery; ST = stent thrombosis; TLR = target lesion revascularization; TVR = target vessel revascularization. American Journal of Cardiology  , DOI: ( /j.amjcard ) Copyright © 2011 Elsevier Inc. Terms and Conditions

3 Figure 2 Adverse events by high-sensitivity C-reactive protein quartiles 1 (blue bars), 2 (red bars), 3 (green bars), and 4 (purple bars). Abbreviations as in Figure 1. American Journal of Cardiology  , DOI: ( /j.amjcard ) Copyright © 2011 Elsevier Inc. Terms and Conditions

4 Figure 3 Adverse events according to bare metal stent plus high-sensitivity C-reactive protein level ≤2 mg/L (blue bars), drug-eluting stent plus high-sensitivity C-reactive protein level ≤2 mg/L (red bars), drug-eluting stent plus high-sensitivity C-reactive protein level >2 mg/L (green bars), and bare metal stent plus high-sensitivity C-reactive protein level >2 mg/L (purple bars) (p <0.001). Abbreviations as in Figure 1. American Journal of Cardiology  , DOI: ( /j.amjcard ) Copyright © 2011 Elsevier Inc. Terms and Conditions

5 Figure 4 Kaplan–Meier for event-free survival (log function) demonstrated significant differences (p = 0.004) for occurrence of myocardial infarction and death, where the following order was increasingly detrimental: bare metal stent plus high-sensitivity C-reactive protein ≤2 mg/L (blue line), drug-eluting stent plus high-sensitivity C-reactive protein ≤2 mg/L (green line), drug-eluting stent plus high-sensitivity C-reactive protein >2 mg/L (yellow line), bare metal stent plus high-sensitivity C-reactive protein >2 mg/L (purple line). American Journal of Cardiology  , DOI: ( /j.amjcard ) Copyright © 2011 Elsevier Inc. Terms and Conditions


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