1. 1.08 (0.77, 1.51)
0.93 (0.74, 1.16)
0.84 (0.63, 1.12)
1.29 (0.24, 6.91)
1.10 (0.80, 1.52)
0.93 (0.74, 1.17)
1.50 (0.27, 8.34)
1.12 (0.39, 3.23)
0.81 (0.60, 1.10)
1.08 (0.77, 1.52) 1 .1 .5 5 10
Study
Relative ratio (95% CI)
p value for
heterogeneity
No. of trial
< 1y PD
ACEI
< 200
>= 60y
Sample size
Active agent
>= 200
>= 1y
Age
< 60y HD
ARB
Follow-up year
Placebo
Dialysis modality
RASI type
Control group 2 6 4 7 3
p = 0.26
p = 0.19
p = 0.59
p = 0.73
p = 0.71
p = 0.27
Favours ACEI/ARB
Favours Control
Fig. S1. Subgroup analysis for the relationship between all-cause mortality and the use of ACEI/ARB.