1. IκB kinase inhibition as a potential treatment of osteoarthritis – results of a clinical proof- of-concept study 
K. Grothe, K. Flechsenhar, T. Paehler, O. Ritzeler, J. Beninga, J. Saas, M. Herrmann, K. Rudolphi 
Osteoarthritis and Cartilage 
Volume 25, Issue 1, Pages (January 2017)
DOI: /j.joca
Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

2. Fig. 1
Illustration of the mode of action of the IKK-inhibitor SAR
Osteoarthritis and Cartilage  , 46-52DOI: ( /j.joca )
Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

3. Fig. 2
Graphic illustration of the concentration of SAR in the plasma of study participants.
Osteoarthritis and Cartilage  , 46-52DOI: ( /j.joca )
Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

4. Fig. 3
Relative Change [%] from baseline from Day 1 to Day 168 – Mean (±SEM).
Osteoarthritis and Cartilage  , 46-52DOI: ( /j.joca )
Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

5. Fig. 4
Relative Change [%] from baseline from Day 1 to Day 168 – Mean (±SEM).
Osteoarthritis and Cartilage  , 46-52DOI: ( /j.joca )
Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

6. Fig. 5
Graphic illustration of the concentration of SAR in the plasma of study participants.
Osteoarthritis and Cartilage  , 46-52DOI: ( /j.joca )
Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

7. Fig. 6
Illustration of concentrations of SAR in plasma in study participants depending on the subgroup of patients, i.e., those with knee effusion at baseline and those without effusion.
Osteoarthritis and Cartilage  , 46-52DOI: ( /j.joca )
Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions