1. Review Chromosome Patterns
At the end of mitosis’ telophase a cell has an unreplicated copy of each chromosome.
The chromosomes look like sticks and are called chromatids.
During interphase chromosomes uncoil into chromatin and replicate. So at prophase the replicated chromosomes look like X’s and have 2 sister chromatids joined at a centromere.

2. Mitosis – chromosome shapes reviewed
What do the two chromosome colours represent?
What does n equal in this cell?
Which phases show replicated chromosomes?
When do the sister chromatids separate?
Maternal and paternal chromosomes
n = 2
Prophase and metaphase
Anaphase

3. Meiosis – V3
Meiosis is the process by which sex cells or gametes are made. This process is also called gametogenesis.
During meiosis the number of chromosomes per cell is reduced by half making haploid gametes.
When a haploid sperm fertilizes the haploid egg a diploid zygote is formed. This is the first body cell.

5. Meiosis I and II Meiosis has two distinct stages.
Meiosis I – reduction division, one diploid cell forms 2 haploid cells by separating homologous chromosomes
Meiosis II – each haploid cell divides again by separating sister chromatids

6. Meiosis - Prophase I
Nuclear membrane dissolves, and the centrioles move to opposite poles.
Each chromosome pairs with its corresponding homologous chromosome to form a tetrad.
There are 4 sister chromatids in a tetrad.
The pairing of homologous chromosomes is the key to understanding meiosis.
Crossing-over probably occurs here.

7. Meiosis - Metaphase I
Homologous pairs of chromosomes, called a tetrad, line up at the equatorial plate.
This is a DOUBLE LINE of chromosomes!!
Spindle fibers from the centrioles attach to the centromeres of the chromosomes.

8. Meiosis - Anaphase I
The spindle fibers pull the homologous chromosomes toward opposite ends of the cell.
Why is this called the reduction division?
The homologous chromosomes are separated. This will form haploid cells from diploid cells.

9. Meiosis - Telophase I Nuclear membranes might reform.
Cytoplasm divides after telophase, resulting in TWO haploid daughter cells.

10. Meiosis - Prophase II
The second part of meiosis resembles mitosis except the cells are haploid.
The centrioles are replicated.
Centrioles in the 2 new cells move to opposite poles.
New spindle fibres form and attach to centromeres.

11. Meiosis - Metaphase II
The chromosomes are in a single line on the equatorial plate.
This is similar to metaphase in mitosis.

12. Meiosis - Anaphase II
Spindle fibres separate sister chromatids which move to opposite ends of the cell.

13. Meiosis - Telophase II
Cytoplasm separates, resulting in 4 haploid cells.
Meiosis NOT a cycle like mitosis but forms haploid egg and sperm cells.

14. Meiosis forms gametes
In males, meiosis or spermatogenesis results in 4 sperm cells.
In females, meiosis or oogenesis results in 1 egg cell for reproduction and three polar bodies, which are not used in reproduction.
The one egg cell has all the cytoplasm, while the polar bodies only have a haploid copy of the chromosomes.
Haploid sperm will fertilize a haploid egg to form the zygote, the first diploid body cell.

16. Comparing Mitosis and Meiosis
Starting # cells?
Where does this occur?
Are ending cells genetically identical?
Ending # of cells?
Are end cells 2n or n?
Ending cells haploid or diploid?
Is it a cycle? 16

17. Comparing Mitosis and Meiosis
Starting # cells?
1 diploid
Starting n? 4n
Where does this occur?
Body or somatic cells
Ovary or testes
Are ending cells genetically identical?
Genetically identical
Genetically different
Ending # of cells? 2 4
Are end cells 2n or n? 2n n
Ending cells haploid or diploid?
Diploid
Haploid
Is it a cycle?
YES NO 17