1. BLA Biology ( )
June 5th 2017

2. COPY DATE, TOPIC & OBJECTIVE ON PG. 66 Date: 6.5.17
Ch. 12. Gene Action
Deadline to Turn in Ch.11 &12 related past work today!!!!!
Ch. 11 & 12 Test, Wednesday Jun 7th 2017
Topic(s) – 1) DNA Replication (Wrap up) 2) The Central Dogma 3) Gene Expression: RNA, Transcription, Translation & Protein Synthesis (Day 1)
Objective: SWBAT 1) Wrap up steps in DNA replication; 2) Learn about structure & function of RNA; 3) Get and introduction to the Central Dogma of Molecular Biology
COPY HW, COPY& ANS.DO-NOW; COPY & ANS. EXIT TICKET ON PG. 65
HW: Organize your science journal, Unfinished CW/HW (if any), ET
Work on Ch.11 &12 Study Guide
Do Now: Take out Summary of DNA Replication Wksht. from Friday
What does RNA stand for? Create a T-chart and write 5 differences between DNA and RNA
CW: DNA Replication (Wrap up); RNA and introduction to the central dogma of Molecular Biology
RNA & Transcription -
Exit Ticket (Refer to Slip): 1) Create a T-chart and describe the S&F of the 3 types of RNA
2) Give a diagrammatic representation of the Central Dogma of Molecular Biology. Appropriately label and define transcription & translation in this diagram
Body of Lesson: (DO NOT HAVE TO COPY)
1) DN & DN Debrief ) DNA Replication (Wrap up); RNA and introduction to the central dogma of Molecular Biology ) ET

4. PCR (POLYMERASE CHAIN REACTION)

9. Structure of RNA
Like DNA, RNA is a polymer of nucleotides. In an RNA nucleotide, the sugar ribose is attached to a phosphate molecule and to a base, either G, U, A, or C. Notice that in RNA, the base uracil replaces thymine as one of the pyrimidine bases. RNA is single-stranded, whereas DNA is double-stranded.

10. Structural & Functional difference between DNA & RNA

11. Three Types of RNA .
Messenger RNA (mRNA) copies DNA’s code & carries the genetic information to the ribosomes
Ribosomal RNA (rRNA), along with protein, makes up the ribosomes
Transfer RNA (tRNA) transfers amino acids to the ribosomes where proteins are synthesized

13. Messenger RNA Long Straight chain of Nucleotides Made in the Nucleus
Copies DNA & leaves through nuclear pores
Contains the Nitrogen Bases A, G, C, U ( no T )

14. Messenger RNA (mRNA) Carries the information for a specific protein
Made up of 500 to 1000 nucleotides long
Sequence of 3 bases called codon
AUG – methionine or start codon
UAA, UAG, or UGA – stop codons

15. Ribosomal RNA (rRNA)
rRNA is a single strand 100 to 3000 nucleotides long
Globular in shape
Associates with proteins to form ribosomes
Site of protein Synthesis

16. Transfer RNA (tRNA) Clover-leaf shape
Single stranded molecule with attachment site at one end for an amino acid
Opposite end has three nucleotide bases called the anticodon
amino acid
attachment site U A C
anticodon