1. Effects of metformin versus ethinyl-estradiol plus cyproterone acetate on ambulatory blood pressure monitoring and carotid intima media thickness in women with the polycystic ovary syndrome 
Manuel Luque-Ramírez, M.D., Covadonga Mendieta-Azcona, M.D., Francisco Álvarez-Blasco, M.D., Héctor F. Escobar-Morreale, M.D., Ph.D. 
Fertility and Sterility 
Volume 91, Issue 6, Pages (June 2009)
DOI: /j.fertnstert
Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

2. Figure 1
Changes in average daytime, nighttime, and 24-hour blood pressure and heart rate recordings of polycystic ovary syndrome patients treated with Diane35 Diario or metformin for 24 weeks. Data are mean ± standard error of the mean. Eleven patients completed the metformin arm (this arm had a large dropout rate, and the baseline ambulatory blood pressure monitoring recording was missing for one patient); the intention-to-treat analysis included all of the patients treated with metformin (n = 18). ∗P<.05 for the interaction between the arms of treatment, in both analysis of patients who completed the study and in intention-to-treat analysis.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

3. Figure 2
Changes in the physiologic nocturnal decrease in systolic, diastolic, and mean blood pressure of polycystic ovary syndrome patients treated with Diane35 Diario or metformin for 24 weeks. Data are mean ± SEM. Eleven patients completed the metformin arm (this arm had a large dropout rate, and the baseline ambulatory blood pressure monitoring recording was missing for one patient); the intention-to-treat analysis included all of the patients treated with metformin (n = 18).
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

4. Figure 3
Changes in common carotid intima-media thickness of PCOS patients submitted to treatment with Diane35 Diario (n = 15) or metformin (n = 19) for 24 weeks in the whole of patients. Symbols and error bars are mean ± SEM. The shaded area represents the mean ± SEM of the nonhyperandrogenic control group. Because of the large drop-out rate in the metformin arm, the Figures show the analysis of the patients completing the study (n = 12) and an intention-to-treat analysis including all the patients treated with metformin (n = 19). ∗P<.05 compared with the control group of healthy women irrespective of the arm of treatment.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions