1. Volume 14, Issue 6, Pages 454-458 (November 2014)
Electron-microscopic evidence of mitochondriae containing macroautophagy in experimental acute pancreatitis: Implications for cell death 
Tony George Jacob, Vipin Iyani Sreekumar, Tara Sankar Roy, Pramod Kumar Garg 
Pancreatology 
Volume 14, Issue 6, Pages (November 2014)
DOI: /j.pan
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2. Fig. 1
Photomicrographs of H&E stained, 5μ thick sections of the pancreas derived from mice of Groups 2 (‘A’ and ‘B’) and 3 (‘C’ and ‘D’). ‘C’ when compared to ‘A’ shows more inflammatory infiltration (arrows) and even sites of microhemorrhages (He). G2 also shows more apoptosis (Ap) than necrosis (Ne).
Pancreatology  , DOI: ( /j.pan )
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3. Fig. 2
Electron micrograph of a normal pancreatic acinar cell showing normal mitochondria [M], nucleus [N], zymogen granules [Z] and rough endoplasmic reticulum [rER]. Scale bar = 1 μm.
Pancreatology  , DOI: ( /j.pan )
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4. Fig. 3
Electron micrograph of the pancreatic acinar cell from a mouse that received 4 injections of caerulein showing zymogen granules [Z], mitochondria [M] and a large autophagosome [arrows] containing abnormal mitochondria [aM], organellar membranes [OM] and zymogen granules [Zy]. N.B. the zymogen granule marked with ‘Z’ appears to be docking on the autophagosomal membrane. Scale bar = 1 μm.
Pancreatology  , DOI: ( /j.pan )
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5. Fig. 4
Photomicrograph of the TEM of the pancreas derived from an animal that received 8 injections of caerulein showing a large autophagosome [Au] containing a mitochondria [M] showing dilated and abnormal cristae [inset]. The dashed arrow indicates a nuclear fragment within the autophagosome. Scale bar = 1 μm [inset = 200 μm].
Pancreatology  , DOI: ( /j.pan )
Copyright © 2014 IAP and EPC Terms and Conditions

6. Fig. 5
Electron micrograph of a pancreatic acinar cell from a mouse that received 8 hourly injections of caerulein, showing a nucleus [N] with peripheral condensation of chromatin indicative of apoptosis, deformed rough endoplasmic reticulum [rER] and an autophagosome [inset] containing zymogen granules [Z] and mitochondria edema and deformed cristae. Scale bar = 2 μm.
Pancreatology  , DOI: ( /j.pan )
Copyright © 2014 IAP and EPC Terms and Conditions

7. Fig. 6
Electron micrograph of a pancreatic acinar cell from a mouse that received 8 hourly injections of caerulein, showing an autophagosome containing abnormal mitochondriae (aM). The double membrane of the autophagosome can be appreciated (arrow).
Pancreatology  , DOI: ( /j.pan )
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8. Fig. 7
Photomicrographs of H&E stained, 5μ thick sections of the pancreas derived from rats that were given saline infusion into the main pancreatic duct (‘A’ and ‘B’) and Na-taurocholate (‘C’ and ‘D’). The saline infusion produces intralobular edema and mild inflammation (In); whereas infusion with Na-taurocholate produces more edema, inflammation and even microhemorrhages (He). PD = interlobular pancreatic duct.
Pancreatology  , DOI: ( /j.pan )
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9. Fig. 8
Transmission electronmicrograph of a section of the pancreas derived from a rat that was given saline infusion into the main pancreatic duct showing a large macroautophagosome containing zymogen granules, dilated RER and mitochondriae. Inset: magnified view of the area in the box, showing the cristae of the mitochondria (M).
Pancreatology  , DOI: ( /j.pan )
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10. Supplementary Fig. 1
Transmission electronmicrograph of a section of the pancreas derived from a rat that was given saline infusion into the main pancreatic duct showing a pancreatic acinar cell with two nuclei, expanded RER and apical zymogen granules.
Pancreatology  , DOI: ( /j.pan )
Copyright © 2014 IAP and EPC Terms and Conditions

11. Supplementary Fig. 2
Transmission electronmicrograph of a section of the pancreas derived from a rat that was given Na-taurocholate infusion into the main pancreatic duct showing a large macroautophagosome (Au). The arrows indicate the double-layered membrane that is enclosing the autophagosome. ‘M’ indicates normal mitochondriae.
Pancreatology  , DOI: ( /j.pan )
Copyright © 2014 IAP and EPC Terms and Conditions

12. Supplementary Fig. 3
Electron micrograph of a pancreatic acinar cell from a mouse that received 8 hourly injections of caerulein, showing necrotic morphology-the arrows indicate a disrupted cell membrane and basement membrane; abnormal mitochondriae (M), rough endoplasmic reticulum (rER). The boundaries of the autophagosome have become blurred but they still contain zymogen granules (Z).
Pancreatology  , DOI: ( /j.pan )
Copyright © 2014 IAP and EPC Terms and Conditions