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Endocrine Pharmacology Review

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Presentation on theme: "Endocrine Pharmacology Review"— Presentation transcript:

1 2003-2004 Endocrine Pharmacology Review
28 May :02 PM

2 Alpha-glucosidase inhibitor Inhibitor of intestinal glucose absorption
Acarbose Oral hypoglycemic Alpha-glucosidase inhibitor Inhibitor of intestinal glucose absorption

3 Adrenocorticotropin (ACTH)
Anterior pituitary hormone Anticonvulsant Stimulates synthesis and release of cortisol

4 Adrenocorticosteroid Mineralocorticoid
Aldosterone Adrenocorticosteroid Mineralocorticoid

5 Antineoplastic Immunosuppressive
Aminoglutethimide Antineoplastic Immunosuppressive Glucocorticoid antagonist Aromatase inhibitor (decreases steroid synthesis)

6 Antineoplastic Antiestrogen
Anastrozole Antineoplastic Antiestrogen Aromatase inhibitor

7 Hormone Insulin analogue
Aspart insulin Hormone Insulin analogue Ultra short acting

8 Betamethasone Adrenocorticosteroid Glucocorticoid
Anti-inflammatory steroid Not by inhalation

9 Androgen receptor antagonist
Bicalutamide Antiandrogen Androgen receptor antagonist

10 Dopamine (D2) agonist Inhibits prolactin release
Bromocriptine Antiparkinson Dopamine (D2) agonist Inhibits prolactin release

11 Oxytocic prostaglandin
Carboprost Oxytocic prostaglandin Uterine stimulant

12 Gonadotropin releasing hormone antagonist Synthetic GnRH analogue
Cetrorelix Gonadotropin releasing hormone antagonist Synthetic GnRH analogue

13 Sulfonylurea Insulinotropic
Chlorpropamide Oral hypoglycemic Sulfonylurea Insulinotropic

14 Partial estrogen agonist Ovulation inducing agent
Clomiphene Partial estrogen agonist Ovulation inducing agent

15 Conjugated estrogens Estrogen Used for HRT

16 Adrenocorticosteroid Glucocorticoid
Corticosterone Adrenocorticosteroid Glucocorticoid

17 Cortisol (Hydrocortisone)
Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid

18 Corticotropin-releasing Hormone (CRH)
Hypothalamic hormone Stimulates release of ACTH and -endorphin from the anterior pituitary

19 19-nor testosterone analogue Combination oral contraceptive
Desogesterel Progestin 19-nor testosterone analogue Combination oral contraceptive

20 Dexamethasone Adrenocorticosteroid Glucocorticoid Antineoplastic Antiemetic Anti-inflammatory steroid Not by inhalation

21 Nonsteroidal estrogen
Diethylstilbestrol Nonsteroidal estrogen

22 Natural male gonadal steroid
Dihydrotestosterone Androgen Natural male gonadal steroid

23 Androgen synthesis inhibitor 5-reductase inhibitor
Dutasteride Antiandrogen Androgen synthesis inhibitor 5-reductase inhibitor

24 Oxytocic ergot alkaloid
Ergonovine Oxytocic ergot alkaloid Uterine stimulant

25 Transdermal formulation
Estraderm Estrogen Transdermal formulation

26 Primary natural female gonadal steroid
Estradiol Estrogen Primary natural female gonadal steroid

27 Natural female gonadal steroid
Estriol Estrogen Natural female gonadal steroid

28 Natural female gonadal steroid
Estrone Estrogen Natural female gonadal steroid

29 Synthetic female gonadal steroid Combination oral contraceptive
Ethinyl estradiol Estrogen Synthetic female gonadal steroid Combination oral contraceptive

30 19-nor testosterone analog Combination oral contraceptive
Ethynodiol diacetate Progestin 19-nor testosterone analog Combination oral contraceptive

31 Antineoplastic Antiestrogen
Exemestane Antineoplastic Antiestrogen Aromatase Inhibitor

32 Androgen synthesis inhibitor 5-reductase inhibitor
Finasteride Antiandrogen Androgen synthesis inhibitor 5-reductase inhibitor

33 Adrenocorticosteroid Mineralocorticoid
Fludrocortisone Adrenocorticosteroid Mineralocorticoid

34 Antiandrogen Antineoplastic Androgen receptor antagonist
Flutamide Antiandrogen Antineoplastic Androgen receptor antagonist

35 Follicle-Stimulating Hormone (FSH)
Anterior pituitary hormone Regulator of gonadal function

36 Antineoplastic Antiestrogen Estrogen receptor antagonist
Fulvestrant Antineoplastic Antiestrogen Estrogen receptor antagonist

37 Gonadotropin releasing hormone antagonist Synthetic GnRH analogue
Ganirelix Gonadotropin releasing hormone antagonist Synthetic GnRH analogue

38 Hormone Insulin analogue
Glargine insulin Hormone Insulin analogue Long acting

39 Sulfonylurea Insulinotropic
Glimepiride Oral hypoglycemic Sulfonylurea Insulinotropic

40 Sulfonylurea Insulinotropic
Glipizide Oral hypoglycemic Sulfonylurea Insulinotropic

41 Stimulates glycogenolysis, gluconeogenesis and ketogenesis
Glucagon Pancreatic hormone Stimulates glycogenolysis, gluconeogenesis and ketogenesis

42 Sulfonylurea Insulinotropic
Glyburide Oral hypoglycemic Sulfonylurea Insulinotropic

43 Gonadorelin Gonadotropin releasing hormone (GnRH)
Synthetic form of natural GnRH Insulinotropic

44 Gonadotropin-releasing Hormone (GnRH)
Hypothalamic hormone Stimulates release of FSH and LH from the anterior pituitary

45 Antineoplastic Gonadotropin releasing hormone (GnRH) agonist
Goserelin Antineoplastic Gonadotropin releasing hormone (GnRH) agonist

46 Growth Hormone-releasing Hormone (GHRH)
Hypothalamic hormone Stimulates release of growth hormone from the anterior pituitary

47 Growth Hormone Somatotropin (GH)
Anterior pituitary hormone Stimulates insulin-like growth factor I release ( growth at open epiphyses), lipolysis and skeletal muscle growth

48 Gonadotropin releasing hormone (GnRH) agonist Synthetic GnRH analogue
Histrelin Gonadotropin releasing hormone (GnRH) agonist Synthetic GnRH analogue

49 Human Chorionic Gonadotropin (hCG)
Placental hormone Stimulates ovarian progesterone production Maintains placenta Ovulation inducing agent

50 Indomethacin NSAID Analgesic, Anti-inflammatory, Antipyretic
Cyclooxygenase inhibitor Tocolytic Uterine relaxant

51 Iodide Antithyroid Prevents synthesis and release of thyroid hormones (blocks iodine organification) Decreases hyperplasia

52 Hormone Insulin analogue
Lente insulin Hormone Insulin analogue Intermediate acting

53 Antineoplastic Antiestrogen
Letrozole Antineoplastic Antiestrogen Aromatase Inhibitor

54 Antineoplastic Gonadotropin releasing hormone (GnRH) agonist
Leuprolide Antineoplastic Gonadotropin releasing hormone (GnRH) agonist

55 Dopamine precursor Inhibits growth hormone release
Levodopa Antiparkinson Dopamine precursor Inhibits growth hormone release

56 19-nor testosterone analogue Combination oral contraceptive
Levonorgestrel Progestin 19-nor testosterone analogue Combination oral contraceptive

57 Levothyroxine (T4) Thyroid hormone

58 Liothyronine (T3) Thyroid hormone

59 Hormone Insulin analogue
Lispro insulin Hormone Insulin analogue Ultra short acting

60 Lutenizing hormone (LH)
Anterior pituitary hormone Regulator of gonadal function

61 Tocolytic Uterine relaxant
Magnesium sulfate Calcium antagonist Tocolytic Uterine relaxant

62 Synthetic progesterone analogue Contraceptive
Medroxyprogesterone Progestin Synthetic progesterone analogue Contraceptive

63 Gonadotropin Ovulation inducing agent
Menotropin Hormone Gonadotropin Ovulation inducing agent

64 Synthetic female gonadal steroid Combination oral contraceptive
Mestranol Estrogen Synthetic female gonadal steroid Combination oral contraceptive

65 Biguanide Hepatic gluconeogenesis inhibitor
Metformin Oral hypoglycemic Biguanide Hepatic gluconeogenesis inhibitor

66 Prevents synthesis of thyroid hormones (blocks iodine organification)
Methimazol Antithyroid Prevents synthesis of thyroid hormones (blocks iodine organification)

67 Methyltestosterone Androgen Synthetic oral

68 Glucocorticoid antagonist
Metyrapone Glucocorticoid antagonist

69 Progesterone antagonist
Mifepristone (RU-486) Progesterone antagonist

70 Alpha-glucosidase inhibitor Inhibits intestinal glucose absorption
Miglitol Oral hypoglycemic Alpha-glucosidase inhibitor Inhibits intestinal glucose absorption

71 Gonadotropin releasing hormone (GnRH) agonist
Nafarelin Gonadotropin releasing hormone (GnRH) agonist

72 Meglitinide Insulinotropic
Nateglinide Oral hypoglycemic Meglitinide Insulinotropic

73 19-nor testosterone analogue Combination oral contraceptive
Norethynodrel Progestin 19-nor testosterone analogue Combination oral contraceptive

74 19-nor testosterone analogue Combination oral contraceptive
Norgestimate Progestin 19-nor testosterone analogue Combination oral contraceptive

75 19-nor testosterone analogue Combination oral contraceptive
Norgestrel Progestin 19-nor testosterone analogue Combination oral contraceptive

76 Hormone Insulin analogue
NPH insulin Hormone Insulin analogue Intermediate acting

77 Somatostatin analogue Peptide hormone inhibitor
Octreotide Somatostatin analogue Peptide hormone inhibitor Decreases growth hormone secretion Decreases gastric and pancreatic secretions

78 Hypothalamic (posterior pituitary) hormone
Oxytocin Hypothalamic (posterior pituitary) hormone Uterine stimulant

79 Maintains plasma Ca2+ concentrations
Parathyroid hormone Hormone Maintains plasma Ca2+ concentrations

80 Thiazolidinedione Insulin sensitizer
Pioglitazone Oral hypoglycemic Thiazolidinedione Insulin sensitizer

81 Prednisone Adrenocorticosteroid Glucocorticoid Antineoplastic
Anti-inflammatory Not by inhalation

82 Natural female progestin
Progesterone Progestin Natural female progestin

83 Anterior pituitary hormone Regulator of lactation
Prolactin Anterior pituitary hormone Regulator of lactation

84 Prevents synthesis of thyroid hormones (blocks iodine organification)
Propylthiouracil Antithyroid Prevents synthesis of thyroid hormones (blocks iodine organification)

85 Prostaglandin E2 (PGE2) Dinoprostone (Dinoprost)
Oxytocic prostaglandin Inflammatory mediator Cyclooxygenase product of arachidonate metabolism Uterine stimulant Cervical ripener

86 Radioactive Iodide (131I)
Antithyroid Destruction of thyroid parenchyma

87 Selective estrogen receptor modulator (SERM)
Raloxifene Antiestrogen Selective estrogen receptor modulator (SERM)

88 Short acting preparation
Regular insulin Insulin analog Short acting preparation

89 Meglitinide Insulinotropic
Repaglinide Oral hypoglycemic Meglitinide Insulinotropic

90 Sympathomimetic 2 adrenergic agonist Tocolytic Uterine relaxant
Ritodrine Sympathomimetic 2 adrenergic agonist Tocolytic Uterine relaxant

91 Thiazolidinedione Insulin sensitizer
Rosiglitazone Oral hypoglycemic Thiazolidinedione Insulin sensitizer

92 Phosphodiesterase-5 inhibitor Promotes erection
Sildenafil Vasodilator Phosphodiesterase-5 inhibitor Promotes erection

93 Somatostatin Somatotropin Release-inhibiting Hormone (SRIH)
Hypothalamic hormone Inhibits release of growth hormone from the anterior pituitary

94 Growth hormone analogue
Somatrem Growth hormone analogue Stimulates insulin-like growth factor I release ( growth at open epiphyses), lipolysis and skeletal muscle growth

95 Growth hormone analogue
Somatropin Growth hormone analogue Stimulates insulin-like growth factor I release ( growth at open epiphyses), lipolysis and skeletal muscle growth

96 Potassium sparing diuretic Antiandrogen
Spironolactone Potassium sparing diuretic Antiandrogen Aldosterone receptor antagonist Androgen receptor antagonist Testosterone synthesis inhibitor Antihypertensive Heart failure treatment

97 Phosphodiesterase-5 inhibitor Promotes erection
Tadalafil Vasodilator Phosphodiesterase-5 inhibitor Promotes erection

98 Antineoplastic Antiestrogen Estrogen receptor anatagonist
Tamoxifen Antineoplastic Antiestrogen Estrogen receptor anatagonist

99 Terbutaline Sympathomimetic 2 adrenergic agonist
Short acting bronchodilator Tocolytic Uterine relaxant

100 Natural male gonadal steroid
Testosterone Androgen Natural male gonadal steroid

101 Testosterone cypionate
Androgen Synthetic depot formulation

102 Testosterone enanthate
Androgen Synthetic depot formulation

103 Testosterone propionate
Androgen Synthetic depot formulation

104 Thyrotropin-releasing Hormone (TRH)
Hypothalamic hormone Stimulates release of thyroid stimulating hormone (TSH) from the anterior pituitary

105 Thyrotropin Thyroid-stimulating Hormone (TSH)
Anterior pituitary hormone Stimulates production of thyroxine (T4), triiodothyronine (T3) and thyroglobulin

106 Sulfonylurea Insulinotropic
Tolbutamide Oral hypoglycemic Sulfonylurea Insulinotropic

107 Selective estrogen receptor modulator (SERM)
Toremifene Estrogen antagonist Selective estrogen receptor modulator (SERM)

108 Hormone Insulin analogue
Ultralente insulin Hormone Insulin analogue Long acting

109 Phosphodiesterase-5 inhibitor Promotes erection
Vardenafil Vasodilator Phosphodiesterase-5 inhibitor Promotes erection


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