1. How to Navigate the NCTN and Participate in Imaging Research
Wendy Smith, BS, RTRCV, CCRP Rhode Island Hospital Diagnostic Imaging Research

2. Poll Imaging Department and not Cancer Center? On the CTSU roster?
Enrolling patients in NCTN trials?
Are currently working on?
Alliance A011101/ACRIN 6694
E4112
EA1141

3. Objectives: Share insight into Imaging Research on the NCTN
Review experience of two imaging sites to participate in NCTN (struggles and successes)
Tools/steps to get you on the CTSU roster and enrolling into NCTN trials
Questions/Answers

4. Insight: National Clinical Trials Network (NCTN)
NCI asked the 9 Adult cooperative groups asked to merge and pare down to 4 adult groups
New groups and NCTN structure launched March 1st 2014
Alliance for Clinical Trials in Oncology
ECOG-ACRIN Cancer Research Group
NRG Oncology
SWOG
Children's Oncology Group (COG)
Imaging

5. New Structure for NCI research
Lead Academic Participating Sites (LAPS)
NCI Community Oncology Research Program (NCORP)
ACRIN Imaging Research sites not part of LAPS or NCORP
NCTN
LAPS
NCORP ?

6. Experience: Rhode Island Hospital
700+ Bed - Level 1 trauma center with Comprehensive Cancer Center
Imaging Research
Member of ACRIN since 1998
Enrolled over 1400 subjects into ACRIN trials
Comprehensive Cancer center
Member of CALGB and RTOG

7. Experience: Rhode Island Hospital Imaging- NCTN
Signed purchase services agreement for Imaging to be part of EA -2014
Cancer center agreed to put us on the roster for RI005- site can only have one site number on the roster.
Began our first NCTN protocol Aug 2015

8. Continued challenges- Logistical vs. Financial
Who opens a trial at RIH, Coop CA Center or DI?
Conflicting interests DI interested, Oncology not, can you do the trial?
Financial
One agreement between the Institution and NCTN
Where does the money go?
How do you transfer it to your department?
Will the CA Center take a cut of imaging reimbursement?

10. Experience: Clinical Radiologists
Tracy Petro AAS, CTR, CCRP Clinical Research Coordinator Clinical Radiologists Springfield, IL

11. Clinical Radiologists
Private Radiology group servicing 40 offices and 32 Hospitals including Memorial Medical Center (in Illinois, Missouri, Iowa and Indiana)
74 radiologists- all board certified in their specialties
All imaging modalities including- PET, CT and MRI
30+ radiologists involved in research
25 years participating in ACRIN trials

12. Clinical Radiologists
Participated in ACRIN trials including:
6651 Pre-treatment Imaging Eval of Cervical CA
6654 CT Colonography Trial
6667 MRI Contralateral Breast
6685 FDG PET- Head/Neck CA
7151 Extra Colonic Findings
Just to name a few…..

13. Quandary post restructure of Cooperative groups
Pre- NCTN
Member of ACRIN since inception
CCOP site for Memorial Medical Center, Springfield, IL
Post- NCTN
Member of ACRIN- not automatically member of EA
Memorial Medical Center now NCORP- won’t include Clinical Radiologists on their roster.
What to do next and how to participate?

14. ECOG- ACRIN Find a home (membership) How to get on a roster? Can’t?
Sign purchase services agreement with EA 2013
How to get on a roster? Can’t?
Can’t participate in any NCTN trials until on the roster

15. NCTN- develop a method to roster sites not included in LAPS or NCORP
Additional agreement?
Site ID for Clinical Radiologist
PI and “Lead Clinical Research Professional” place on roster
Almost there!