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Temozolomide-related acute lymphoblastic leukemia with translocation (4;11)(q21;q23) in a glioblastoma patient  Kuan-Nien Chou, Yu-chieh Lin, Ming-Ying.

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Presentation on theme: "Temozolomide-related acute lymphoblastic leukemia with translocation (4;11)(q21;q23) in a glioblastoma patient  Kuan-Nien Chou, Yu-chieh Lin, Ming-Ying."— Presentation transcript:

1 Temozolomide-related acute lymphoblastic leukemia with translocation (4;11)(q21;q23) in a glioblastoma patient  Kuan-Nien Chou, Yu-chieh Lin, Ming-Ying Liu, Ping-Ying Chang  Journal of Clinical Neuroscience  Volume 21, Issue 4, Pages (April 2014) DOI: /j.jocn Copyright © 2013 Elsevier Ltd Terms and Conditions

2 Fig. 1 (A) Peripheral blood smear showing blasts with scant cytoplasm (Wright–Giemsa; original magnification × 200) (circles). (B) Bone marrow biopsy showing hypercellularity of 60% (hematoxylin and eosin stain; original magnification × 200). (C) Bone marrow biopsy showing no terminal deoxynucleotidyl transferase reactivity of the blasts (original magnification × 400). (D) Bone marrow biopsy showing no immunoreactivity for CD20 (original magnification × 400). (E) Bone marrow biopsy showing CD79a expression (original magnification × 400). Journal of Clinical Neuroscience  , DOI: ( /j.jocn ) Copyright © 2013 Elsevier Ltd Terms and Conditions

3 Fig. 2 Cytogenetic study of the bone marrow with G-banding, indicating translocation involving chromosomes 4q21 and 11q23, t (4;11) (q21;q23) (arrow). Journal of Clinical Neuroscience  , DOI: ( /j.jocn ) Copyright © 2013 Elsevier Ltd Terms and Conditions


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