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A. Relationship between serum-free thyroxine by dialysis (FT4) ng/dL and log10 TSH in euthyroid, hyperthyroid, hypothyroid, and T4-suppressed euthyroid individuals. Note that for each unit change in T4 there is a logarithmic change in TSH. B. Relationship between FT4 by dialysis and log10 TSH in normal subjects and subjects with various illnesses including primary hypothyroidism, central hypothyroidism and non–levothyroxine-suppressed TSH, levothyroxine-treated congenital hypothyroidism, TSH-secreting tumors, thyroid hormone resistance, nonthyroidal illness, and nonpituitary hyperthyroidism. (Reproduced with permission from Kaptein EM. Clinical applications of free thyroxine determinations. Clin Lab Med Sep;13(3): ) Source: The Thyroid Gland, Greenspan's Basic & Clinical Endocrinology, 10e Citation: Gardner DG, Shoback D. Greenspan's Basic & Clinical Endocrinology, 10e; 2017 Available at: Accessed: October 18, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved
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