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Wednesday March 22, 2017 I can: Agenda Catalyst HW: IP: Mutations

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Presentation on theme: "Wednesday March 22, 2017 I can: Agenda Catalyst HW: IP: Mutations"— Presentation transcript:

1 Wednesday March 22, 2017 I can: Agenda Catalyst HW: IP: Mutations
explain how mutations affect protein synthesis Agenda (10) Catalyst (30) Alien Encounters! (10) GN: Mutations (15) Kahoot (15) IP: Mutations (5) Exit Ticket Catalyst What is nondisjunction? How does this differ from a mutation? What is the polypeptide made from the DNA sequence TACCAAGTA? HW: IP: Mutations

2 Mutations A mutation is a change in a DNA sequence.
Mutation leads to genetic VARIATION!

3 How does a substitution affect the overall amino acid sequence?
Types of Mutations How does a substitution affect the overall amino acid sequence? Substitution – one base is swapped out for another.

4 How does an insertion affect the overall amino acid sequence?
Types of Mutations How does an insertion affect the overall amino acid sequence? Insertion – an extra base pair(s) is added into a new place in the DNA

5 How does a deletion affect the overall amino acid sequence?
Types of Mutations How does a deletion affect the overall amino acid sequence? Deletion – Base pairs in the sequence are lost or deleted

6 Types of Mutations A T G A C G T A A A T C G A C G T A A
Insertions and deletions are called frame shift mutations. DNA is “read” in 3-base codons in/dels change the reading frame A T G A C G T A A A T C G A C G T A A mutation!

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