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Nina Vasavada, Rajiv Agarwal  Kidney International 

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Presentation on theme: "Nina Vasavada, Rajiv Agarwal  Kidney International "— Presentation transcript:

1 Role of excess volume in the pathophysiology of hypertension in chronic kidney disease 
Nina Vasavada, Rajiv Agarwal  Kidney International  Volume 64, Issue 5, Pages (November 2003) DOI: /j x Copyright © 2003 International Society of Nephrology Terms and Conditions

2 Figure 1 Brain natriuretic peptide (BNP) responses after single (A) and multiple (B) doses of torsemide and furosemide therapy for each subject. Closed triangles represent treatment with torsemide; open triangles represent treatment with furosemide. Box plots represent the median, 10th, 25th, 75th, and 90th percentiles of each data set. Ln is natural log. Kidney International  , DOI: ( /j x) Copyright © 2003 International Society of Nephrology Terms and Conditions

3 Figure 2 Plasma renin activity (PRA) (A) and plasma aldosterone (PA) responses after multiple doses of torsemide and furosemide therapy for each subject. Closed triangles represent treatment with torsemide; open triangles represent treatment with furosemide. Box plots represent the median, 10th, 25th, 75th, and 90th percentiles of each data set. Kidney International  , DOI: ( /j x) Copyright © 2003 International Society of Nephrology Terms and Conditions

4 Figure 3 Time course of biophysical and hormonal measurements of volume status during multiple dose study.*P < 0.05 in comparison with baseline measurements by analysis of variance (ANOVA) for systolic blood pressure and Tukey honest significant test for other parameters. Multivariate ANOVA for all comparisons were significant. Kidney International  , DOI: ( /j x) Copyright © 2003 International Society of Nephrology Terms and Conditions


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