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The Role of IVUS for Evaluation & Treatment Optimisation

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Presentation on theme: "The Role of IVUS for Evaluation & Treatment Optimisation"— Presentation transcript:

1 The Role of IVUS for Evaluation & Treatment Optimisation
The Venoplasty Programme The Venoplasty Programme, The Edinburgh Clinic, Scotland

2

3 CAROTID IVUS

4 CAROTID IVUS Irshad K, Reid D, Miller P et al J Endovasc Ther ; 8 :

5 Percutaneous Femoral Vein Access

6 Percutaneous Femoral Vein Access

7 IVUS

8 IVUS

9 Abnormal Valve

10 Abnormal Valve

11 Abnormal Valve

12 A Prospective Study of Clinical Effectiveness & Safety
322 CCSVI Patients with MS undergoing venoplasty

13 MS SPECIFIC FUNCTIONAL COMPOSITE SCORING SYSTEM
National MS Society

14 MS SPECIFIC QUALITY OF LIFE QUESTIONAIRE
National MS Society

15 Magnetic Resonance Imaging

16 Assessment before treatment
& at 6 months Doppler Scan MRI Independent neurological examination scoring (MSFC) Quality of Life scoring

17 322 CCSVI Patients with Multiple Sclerosis
Results 322 CCSVI Patients with Multiple Sclerosis 99 % Technical Success

18 322 CCSVI Patients with Multiple Sclerosis
Results 322 CCSVI Patients with Multiple Sclerosis Complications : 1 transient atrial fibrillation 1 rash 2 extravasation of contrast

19 MSFC SCORE {Z arm average + Z leg average + Z cognitive}/3.0
Pre-treatment score Post treatment score A decrease or an increase in the MSFC score represents, respectively, deterioration or improvement in neurological functions.

20 MSQoL QoL Pre Rx(Physical) ± SD 43.06 ± 17.93
QoL Post Rx(Physical) ± SD ± 22.17 QoL Pre Rx(Mental) ± SD ± 24.01 QoL Post Rx(Mental) ± SD ± 21.57

21 NATIONAL INSTITUE FOR CLINICAL EXCELLENCE DRAFT GUIDELINES

22 Conclusions CCSVI is associated with Multiple Sclerosis
Endovascular treatment is feasible as day case Balloon angioplasty has limitations IVUS is helpful but not essential

23 Venoplasty Programme Donald Reid Khalid Irshad Raj Velu Martin Errington David Kean Barun Majumber Thomas Gilhooly David Pugh Fiona Hassel

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