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Tissues and tissue types

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1 Tissues and tissue types
Tissues are: Collections of specialized cells and cell products organized to perform a limited number of functions Histology = study of tissues The four tissue types are: Epithelial Connective Muscular Nervous

2 Epithelial tissue Includes glands and epithelium Is avascular
Glands are secretory Is avascular Forms a protective barrier that regulates permeability Cells may show polarity

3 Functions of epithelium
Physical protection Control permeability Provide sensation Produce specialized secretions

4 Specializations of epithelium
Perform secretory functions Perform transport functions Maintain physical integrity Ciliated epithelia move materials across their surface

5 The Polarity of Epithelial Cells

6 Maintaining the integrity of epithelium
Cells attach via cell adhesion molecules (CAM) Cells attach at specialized cell junctions Tight junctions Desmosomes Gap junctions

7 Intercellular connections

8 Structure of typical epithelium
Basal lamina attaches to underlying surface Lamina lucida Lamina densa Germinative cells replace short-lived epithelial cells

9 Classification of epithelia
Number of cell layers Simple Stratified Shape of apical surface cells Squamous Cuboidal Columnar

10 Squamous Epithelia

11 Cuboidal Epithelia

12 Cuboidal Epithelia

13 Transitional Epithelium

14 Columnar Epithelia

15 Columnar Epithelia

16 Columnar Epithelia

17

18 Glandular epithelia Exocrine glands Endocrine glands
Secrete through ducts onto the surface of the gland Endocrine glands Release hormones into surrounding fluid

19 Glandular secretions can be:
Merocrine (product released through exocytosis) Apocrine (involves the loss of both product and cytoplasm) Holocrine (destroys the cell)

20 Mechanisms of Glandular Secretion

21 Glands Unicellular Multicellular Individual secretory cells
Organs containing glandular epithelium Classified according to structure

22 A Structural Classification of Exocrine Glands

23 Connective tissue functions:
Establishing a structural framework Transporting fluids and dissolved materials Protecting delicate organs Supporting, surrounding and interconnecting tissues Storing energy reserves Defending the body from microorganisms

24 A Classification of Connective Tissues

25 Connective tissues contain
Specialized cells Matrix Composed of extracellular protein fibers and a ground substance

26 Connective tissue proper
Contains varied cell populations Contains various fiber types A syrupy ground substance

27 Fluid connective tissue
Contains a distinctive cell population Watery ground substance with dissolved proteins Two types Blood Lymph

28 Supporting connective tissues
Less diverse cell population Dense ground substance Closely packed fibers Two types Cartilage Bone

29 Connective tissue proper
Contains fibers, a viscous ground substance, and a varied cell population Fibroblasts Macrophage Adipocytes Mesenchymal cells Melanocytes Mast cells Lymphocytes Microphages

30 Connective tissue proper
Three types of fiber Collagen fibers Reticular fibers Elastic fibers

31 Connective tissue proper
Classified as loose or dense Loose Embryonic mesenchyme, mucous connective tissues Areolar tissue Adipose tissue Reticular tissue Dense Dense regular CT Dense irregular CT

32

33 The Cells and Fibers of Connective Tissue Proper

34 Connective Tissue in Embryos

35 Adipose and Reticular Tissues

36 Dense Connective Tissues

37 Dense Connective Tissues

38 Dense Connective Tissues

39 Fluid connective tissues
Distinctive collections of cells in a fluid matrix Blood Formed elements and plasma Red blood cells, white blood cells and platelets Arteries carry blood away, veins carry to the heart Capillaries allow diffusion into the interstitial fluid Lymph Interstitial fluid entering the lymphatic vessels

40 Formed Elements of the Blood

41 Supporting connective tissues
Cartilage and bone support the rest of the body Cartilage Grows via interstitial and appositional growth Matrix is a firm gel containing chondroitin sulfate Cells called chondrocytes Cells found in lacunae Perichondrium separates cartilage from surrounding tissues Three types: hyaline, elastic and fibrocartilage

42 The Perichondrium and Types of Cartilage

43 The Perichondrium and Types of Cartilage

44 The Perichondrium and Types of Cartilage

45 Bone, or osseus tissue Has osteocytes Little ground substance
Depend on diffusion through canaliculi for nutrients Little ground substance Dense mineralized matrix Surrounded by periosteum

46 Bone

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