1. Introduction of Anti-Histamine

2. Anti-Histamine Diphenhydramine (Benylin®) Pharmaceutical chemistry
Molecular pharmacology
Mechanism of action: 1st generation H1-blocker
Structure-based explanation of Side effects: sedation
Mixtures : Pectolyn antitussive contains dextromethorphan + diphenhydramine + sodium citrate.

3. Anti-Histamine Chlorpheniramine (Polaramine, Allerfin)
Pharmaceutical chemistry
Molecular pharmacology
Mechanism of action: 1st generation H1-blocker
Structure-based explanation of Side effects: sedation
Mixtures: Tussifin contains chlorpheniramine + codeine + glyceryl guaiacolate + potassium citrate + sodium benzoate + liquorice

4. Anti-Histamine Hydroxyzine (Atarax) Pharmaceutical chemistry
Molecular pharmacology
Mechanism of action: 1st generation H1-blocker
Structure-based explanation of Side effects: sedation

5. Anti-Histamine Meclozine (Navidoxine with B6))
Pharmaceutical chemistry
Molecular pharmacology
Mechanism of action: 1st generation H1-blocker
Structure-based explanation of Side effects: sedation

6. Anti-Histamine Dimetindene (Fenistil) Pharmaceutical chemistry
Molecular pharmacology
Mechanism of action: 1st generation H1-blocker
Structure-based explanation of Side effects: sedation

7. Anti-Histamine Triprolidine (Trifed) Pharmaceutical chemistry
Possible Origin
Physiochemical Properties
Idea of Retro-synthesis
Molecular pharmacology
Mechanism of action: 1st generation H1-blocker
Structure-based explanation of Therapeutic uses
Structure-based explanation of Side effects: sedation
Analysis.
Mixtures : Trifed.. Conatins guaiphenesin + pseudoephdrine + triprolidine.

8. Anti-Histamine Oxomemazine (Rectolyn, Rictamol)
Pharmaceutical chemistry
Possible Origin
Physiochemical Properties
Idea of Retro-synthesis
Molecular pharmacology
Mechanism of action: 1st generation H1-blocker
Structure-based explanation of Therapeutic uses
Structure-based explanation of Side effects: sedation
Analysis.
Mixtures : Rectolyn contains Conatins guaiphenesin + paracetamol+ oxomemazine + sodium benzoate.

9. Anti-Histamine Promethazine (Histazin) Pharmaceutical chemistry
Possible Origin
Physiochemical Properties
Idea of Retro-synthesis
Molecular pharmacology
Mechanism of action: 1st generation H1-blocker
Structure-based explanation of Therapeutic uses
Structure-based explanation of Side effects: sedation
Analysis

10. Anti-Histamine Ketotifen (Zaditen) Pharmaceutical chemistry
Possible Origin
Physiochemical Properties
Idea of Retro-synthesis
Molecular pharmacology
Mechanism of action: 1st generation H1-blocker, mast cell stabiliser
Structure-based explanation of Therapeutic uses
Structure-based explanation of Side effects: sedation
Analysis

11. Anti-Histamine Acrivastine (Semprex capsules) Pharmaceutical chemistry
Possible Origin
Physiochemical Properties
Idea of Retro-synthesis
Molecular pharmacology
Mechanism of action: 2nd generation H1-blocker
Structure-based explanation of Therapeutic uses
Structure-based explanation of Side effects
Analysis

12. Anti-Histamine Cetirizine (zyrtec) Pharmaceutical chemistry
Possible Origin
Physiochemical Properties
Idea of Retro-synthesis
Molecular pharmacology
Mechanism of action: 2nd generation H1-blocker
Structure-based explanation of Therapeutic uses
Structure-based explanation of Side effects
Analysis
Levocetrizine( xyzal)

13. Anti-Histamine Loratadine (Claritine) Pharmaceutical chemistry
Possible Origin
Physiochemical Properties
Idea of Retro-synthesis
Molecular pharmacology
Mechanism of action: 2nd generation H1-blocker
Structure-based explanation of Therapeutic uses
Structure-based explanation of Side effects
Analysis

14. Anti-Histamine Desloratadine (Aerius) Pharmaceutical chemistry
Possible Origin
Physiochemical Properties
Idea of Retro-synthesis
Molecular pharmacology
Mechanism of action: 2nd generation H1-blocker
Structure-based explanation of Therapeutic uses
Structure-based explanation of Side effects
Analysis

15. Anti-Histamine Fexofenidine (telfast) Pharmaceutical chemistry
Possible Origin
Physiochemical Properties
Idea of Retro-synthesis
Molecular pharmacology
Mechanism of action: 2nd generation H1-blocker
Structure-based explanation of Therapeutic uses
Structure-based explanation of Side effects
Analysis

16. Anti-Histamine Cimetidine (tagamet, cimedine) Pharmaceutical chemistry
Possible Origin
Physiochemical Properties
Idea of Retro-synthesis
Molecular pharmacology
Mechanism of action: H2-blocker
Structure-based explanation of Therapeutic uses: peptic ulcer, GERD
Structure-based explanation of Side effects: diarrhea, gynecomastia, galactorrhea , low sperm count and Cyto-p450 inhibition.
Analysis

17. Anti-Histamine Famotidine (Pepcidin, Famodar) Pharmaceutical chemistry
Possible Origin
Physiochemical Properties
Idea of Retro-synthesis
Molecular pharmacology
Mechanism of action: H2-blocker, the most potent
Structure-based explanation of Therapeutic uses
Structure-based explanation of Side effects
Analysis

18. Anti-Histamine Ranitidine (Zantac) Pharmaceutical chemistry
Possible Origin
Physiochemical Properties
Idea of Retro-synthesis
Molecular pharmacology
Mechanism of action: H2-blocker
Structure-based explanation of Therapeutic uses
Structure-based explanation of Side effects
Analysis

19. Anti-Histamine Nizatidine (Axid) Pharmaceutical chemistry
Possible Origin
Physiochemical Properties
Idea of Retro-synthesis
Molecular pharmacology
Mechanism of action: H2-blocker
Structure-based explanation of Therapeutic uses
Structure-based explanation of Side effects
Analysis

20. Proton pump inhibitor (PPI)
Omeprazole (losec)
Pharmaceutical chemistry
Possible Origin
Physiochemical Properties
Idea of Retro-synthesis
Molecular pharmacology
Mechanism of action: PPI
Structure-based explanation of Therapeutic uses: Zollinger-Ellison syndrome, GERD, peptic ulcer
Structure-based explanation of Side effects: bacterial viability, B12 deficiency, calcium deficiency, diarrhoea and achlorhydra.
Analysis

21. Proton pump inhibitor (PPI)
Esomeprazole (Nexium)
Pharmaceutical chemistry
Possible Origin
Physiochemical Properties
Idea of Retro-synthesis
Molecular pharmacology
Mechanism of action: PPI
Structure-based explanation of Therapeutic uses
Structure-based explanation of Side effects
Analysis

22. Proton pump inhibitor (PPI)
Lansoprazole (Takepron, Lansec)
Pharmaceutical chemistry
Possible Origin
Physiochemical Properties
Idea of Retro-synthesis
Molecular pharmacology
Mechanism of action: PPI
Structure-based explanation of Therapeutic uses
Structure-based explanation of Side effects
Analysis

23. Proton pump inhibitor (PPI)
Rabeprazole (Parit)
Pharmaceutical chemistry
Possible Origin
Physiochemical Properties
Idea of Retro-synthesis
Molecular pharmacology
Mechanism of action: PPI
Structure-based explanation of Therapeutic uses
Structure-based explanation of Side effects
Analysis

24. Proton pump inhibitor (PPI)
Pantoprazole (Pantop)
Pharmaceutical chemistry
Possible Origin
Physiochemical Properties
Idea of Retro-synthesis
Molecular pharmacology
Mechanism of action: PPI
Structure-based explanation of Therapeutic uses
Structure-based explanation of Side effects
Analysis