1. PDCB BioC for HTS topic Understanding the tech. 01
LCG Leonardo Collado Torres
August 25th, 2010

2. Topics Next generation sequencing technologies 454 SOLiD
Pacific Biosciences
Illumina
Paired-end and Mate-pair
Ion Torrent

3. NGS tech

4. NGS tech

10. 454

14. SOLiD

30. Pacific Biosciences

39. Illumina

43. PE and MP

45. Ion Torrent

53. NGS tech

55. References
1. Mardis, E.R. Next-generation DNA sequencing methods. Annu Rev Genomics Hum Genet 9, (2008).
2. Metzker, M.L. Sequencing technologies [mdash] the next generation. Nat Rev Genet 11, (2010).
3. Tucker, T., Marra, M. & Friedman, J.M. Massively parallel sequencing: the next big thing in genetic medicine. Am. J. Hum. Genet 85, (2009). 4. 5. 6. 7. 8.