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Elevated uric acid and adenosine triphosphate concentrations in bronchoalveolar lavage fluid of eosinophilic pneumonia  Takehito Kobayashi, Kazuyuki Nakagome,

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Presentation on theme: "Elevated uric acid and adenosine triphosphate concentrations in bronchoalveolar lavage fluid of eosinophilic pneumonia  Takehito Kobayashi, Kazuyuki Nakagome,"— Presentation transcript:

1 Elevated uric acid and adenosine triphosphate concentrations in bronchoalveolar lavage fluid of eosinophilic pneumonia  Takehito Kobayashi, Kazuyuki Nakagome, Toru Noguchi, Kiyoko Kobayashi, Yutaka Ueda, Tomoyuki Soma, Kenji Ikebuchi, Hidetomo Nakamoto, Makoto Nagata  Allergology International  Volume 66, Pages S27-S34 (September 2017) DOI: /j.alit Copyright © 2017 Japanese Society of Allergology Terms and Conditions

2 Fig. 1 The concentration of UA in the BALF. The UA concentration (A), the albumin concentration (B), the BALF (UA/albumin)/serum (UA/albumin) ratio (C) and LDH activity (D) in patients with sarcoidosis (n = 35), HP (n = 6), and EP (n = 33). Allergology International  , S27-S34DOI: ( /j.alit ) Copyright © 2017 Japanese Society of Allergology Terms and Conditions

3 Fig. 2 Correlations between UA concentrations and eosinophil count and cytokine concentrations. The relationship between UA concentrations and eosinophil counts (A), EDN (B), IL-5 (C), and eotaxin (D) concentrations in the BALF of EP patients are shown (n = 33). Allergology International  , S27-S34DOI: ( /j.alit ) Copyright © 2017 Japanese Society of Allergology Terms and Conditions

4 Fig. 3 The concentration of ATP in the BALF. (A) The ATP concentration in patients with sarcoidosis (n = 35), HP (n = 6), and EP (n = 33). (B–D) Correlations between ATP concentrations and eosinophil counts (B), UA (C), and IL-5 (D) concentrations in the BALF of EP patients are shown (n = 33). Allergology International  , S27-S34DOI: ( /j.alit ) Copyright © 2017 Japanese Society of Allergology Terms and Conditions

5 Fig. 4 The concentration of IL-33 in the BALF. (A) The IL-33 concentration in patients with sarcoidosis (n = 35), HP (n = 6), and EP (n = 33). (B–D) Correlations between IL-33 concentrations and eosinophil counts (B), UA (C), and ATP (D) concentrations in the BALF of EP patients are shown (n = 33). Allergology International  , S27-S34DOI: ( /j.alit ) Copyright © 2017 Japanese Society of Allergology Terms and Conditions

6 Fig. 5 The concentration of DAMPs in the BALF of AEP and CEP. The UA concentration (A), the ATP concentration (B), the IL-33 concentration (C), LDH activity (D) and BALF (UA/albumin)/serum (UA/albumin) ratio (E) in patients with AEP (n = 14) and CEP (n = 19). Allergology International  , S27-S34DOI: ( /j.alit ) Copyright © 2017 Japanese Society of Allergology Terms and Conditions


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