1. Organoid Models and Applications in Biomedical Research
Nephron 2015;130: DOI: /
Fig. 1. Schematic representation of organoid generation from PSCs. For each class of organoid, this figure shows the germ layer of origin and the main progenitor cell identities or epithelia that can be generated from PSCs by using the in vitro differentiation protocols. These protocols recapitulate the developmental conditions, in terms of ECM and molecular environment, to which ESCs are normally exposed during in vivo organogenesis. More details of PSC differentiation strategies, culture conditions and growth factors used to derive organ-specific progenitor cells are described in the text.
© 2015 S. Karger AG, Basel