1. CORE: Creative thinkers
Enzymes & Proteins
L/O: To what enzymes are and how they are affected by different conditions.
Success Criteria:
A* - Suggest how activation energies are influenced by enzymes
A – Link enzyme functions to the digestive system
B – Explain how the lock and key theory works
C – State what enzymes are and what they do
Starter Recap: Answer the question: “What is a chemical reaction and in what ways can we speed them up?”
CORE: Creative thinkers

2. Enzymes = a biological catalyst
Catalyst = something that can speed up a reaction without being changed or used up in the reaction

3. Enzyme: The Facts! Enzymes are all proteins
All proteins are made of chains of amino acids and these chains fold up to give the unique shapes
Every enzyme has a unique shape that fits onto a substrate at the active site
Enzymes only every catalyse one reaction
Enzymes catalyse protein synthesis and respiration

4. The lock and Key theory

5. Why is shape important? Each enzyme has a different shape
Within the shape is the active site
Only one type of substrate fits into the active site (like a lock and key)
What happens to the substrate after it fits into the active site?

6. Why is shape important?
Draw a cartoon story board of the action of an enzyme of its substrate
Add a step by step of what happens
Label the following:
Active site
Substrate
Product
Enzyme-substrate complex
Enzyme-product complex
Extension: What will happen if the active site changes shape?

7. Self Assess!
Once the substrate is attached to the active site it is turned into the 2 products

8. Self Assess!
Once the substrate is attached to the active site it is turned into the 2 products

9. Self Assess!
Once the substrate is attached to the active site it is turned into the 2 products

10. Self Assess!
Once the substrate is attached to the active site it is turned into the 2 products

11. Self Assess!
Once the substrate is attached to the active site it is turned into the 2 products

12. Step-by-Step Self assess
Shape of the enzyme’s active site is complimentary to the shape of one particular substrate.
The two bind together to form an enzyme-substrate complex.
The reaction between them take place rapidly.
The products are released from the enzyme’s active site.
The enzyme remains unchanged after the reaction

13. True or False

14. Where do Enzymes Work?
Many enzymes work inside body cells but some enzymes work outside body cells.
The digestive enzymes are produced by specialised cells in glands and are then secreted into the gut where they come into contact with food molecules.

15. What do Digestive Enzymes do?
These digestive enzymes catalyse the breakdown of large insoluble food molecules into small soluble molecules that can be absorbed into the blood and transported to other cells in our body

16. Enzymes in Digestion Recap!
Label the parts of the digestive system and what enzymes are found there/ what they do

17. What are the enzymes and how do they work?

18. What are the enzymes and how do they work? Peer assess
Large insoluble food
Enzyme
Produced by
Starch
Amylase (a carbohydrase)
Salivary glands, pancreas & small intestines
Protein
Protease
Stomach, pancreas & small intestines
Fats (lipids)
Lipase
Pancreas & small intestines
Small soluble product
sugars
Amino acids
Glycerol & fatty acids

19. Key Enzymes to know… Starch Maltose Amylase Proteins Amino Acids
Salivary Glands
Pancreas
Small intestine
Starch
Maltose
Amylase
Stomach
Pancreas
Small intestines
Proteins
Amino Acids
Protease
Pancreas
Small intestines
Fats
Fatty Acid + Glycerol
Lipase

20. Quick Check What is a catalyst? Write a definition of an enzyme.
What is the name of the theory that explains how enzymes work
What happens in the small intestine?
Where do we find amylase?
What does protease do?
What does lipase break down fats into?
What is the optimum temperature of most enzymes?
Why have I written “most” in the previous question?

21. What is the activation energy?
Chemical reactions take place when particles collide with enough energy.
The amount of energy required to start a reaction is called the activation energy.
Enzymes lower the amount of activation energy required, so the reaction can proceed at a greater rate.

22. What is the activation energy?
Different reactions have different activation energies. Enzymes LOWER the activation energy for a reaction to occur
reaction (time)
energy (kJ)
Ea without enzyme
Ea with enzyme

23. What have you learnt? Success Criteria:
A* - Suggest how activation energies are influenced by enzymes
A – Link enzyme functions to the digestive system
B – Explain how the lock and key theory works
C – State what enzymes are and what they do
Complete the quiz to see how much you have learnt!
Then peer assess when teacher goes over the answers
10 min

24. What have I learnt? Success Criteria:
A* - Suggest how activation energies are influenced by enzymes
A – Link enzyme functions to the digestive system
B – Explain how the lock and key theory works
C – State what enzymes are and what they do
What have I learnt?
In your books give yourself a grade and explain how you have got that grade, and what you have to do to get a higher grade.
A* -
5 min