1. Blood Typing
Health Occupations

2. Key Terms Antigens: foreign object, pathogen
Antibodies: proteins secreted by lymphocytes
Antibodies bond with antigens = lock and key phenomenon
Antigen = lock antibody = key

3. Blood Type Inherited Each person inherits 2 genes. Dominant genes
Are A and B
Shown as “I”
EX:
Recessive genes O
Shown as “i”
Ex:

4. Punnett Square

5. 4 Blood Types
Blood type is determined by antigens on the surface of RBC A
Only A antigens B
Only B antigens AB
Both A and B antigens O
Neither A or B antigens

6. Your immune system has a tolerance against it own antigens.
(you like your own antigens)
EX: Antigen A type A blood. It will NOT form anti-A antibodies.

7. Blood Type
Antigens on RBC’s
Antibodies in Plasma A
Anti - B B

8. Complete the table showing which blood can be safely transfused from the donor to recipient.
Recipient D O N R
Blood Type A B AB O +

10. Transfusions
Need to mix serum of the patient with the blood cells of the donor.
If Type A gets matched with Type B then antibodies will clump together
If this test is not done hemolysis (rupture of blood cells) can occur

11. Blood Type O Blood Type AB Blood Universal donor
Because it lacks A and B antigens
Type AB Blood
Universal recipients because they lack anti-A and anti-B antibodies.
(they won’t attack new blood coming in)

12. Rh Factor Antigen Found in RBC
Rh- : people who do not have antigens on RBC
Rh+ : people who do have the antigen on RBC
About 85% of Americans are Rh+
If RH + blood is given to Rh- then the body thinks it is an invading pathogen and starts to form antibodies for the lock and key

13. Rh Factor Health Concerns
When an Rh- mother delivers an Rh+ baby, some of the baby’s blood may contact the blood of the mother
The mother’s blood then forms antibodies against Rh+ RBC
If the mother has another Rh+ pregnancy the antibodies will attack the baby’s blood causing erythroblastosis fetalis.