1. Evaluation of Response to Induction-Chemotherapy in Correlation to p53 Genotype in NSCLC stage III; Phase II Study
P53 analysis OP
3 cyles
GEMZAR/ CIS
Response DG
P53 analysis
3 cycles
DOCETAXEL mono
P53 analysis
Failure OP
Purpose:
First prospective evaluation of the impact of
the p53 genotype for response to different CTs

2. Evaluation of response to induction - CT in correlation to p53 genotype in NSCLC stage III ; phase II study Short title: p53 tailored induction therapy
Currently open, accademical study
7 investigational centers in Austria
25 patients accrued, 37 additional needed
Intended by

3. Evaluation of response to induction-CT in correlation to p53 genotype in NSCLC stage III; phase II study
Inclusion
NSCLC Stage IIIA or IIIB
No prior NSCLC therapy
Age 18-70
Exclusion
Recent CT with investigational drug
Second primary CA
Concurrent other tumor therapy