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Protection of CNS 1
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The Brain 3 lbs About the size of two fists Wrinkled
Not solid- kind of mushy to the touch Highly vasculated
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Blood supply & Nutrition
Brain is highly vascular blood delivers O2 and glucose supply and carries away wastes Brain cells have no capacity for anaerobic respiration. They cannot be O2 deprived Brain cells die w/in 5-6 minutes 3
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Protection 1. Bone 2. Meninges 3. Cerebrospinal fluid (CSF)
Cranial bones & vertebral arches 2. Meninges Dura mater Arachnoid mater Pia mater 3. Cerebrospinal fluid (CSF) 4
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Meninges 3 Layers Dura mater (made of two membranes) Arachnoid mater
Pia mater 5
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Dura Mater “Tough Mother” Thick, leathery outer covering
Support, and forms sinus system (where blood drains and returns to the heart) Pain sensitive Has own blood supply – Middle meningeal artery 02 Nov. 2009 CNS1.ppt
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Dura Mater 02 Nov. 2009 CNS1.ppt
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Arachnoid Spongy/fibrous layer between the dura and pia
connective tissue forms projections which give it a spider-web appearance Forms Subarachnoid space Contains CSF 02 Nov. 2009 CNS1.ppt
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Pia Mater Innermost layer
Adheres almost indistinguishably to cortical surface, including sulci and gyri Difficult to see grossly or remove 02 Nov. 2009 CNS1.ppt
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3 Layers of Meninges 02 Nov. 2009 CNS1.ppt
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Cerebrospinal Fluid Produced from blood plasma in choroid plexuses
Located in the subarachnoid space Cushions CNS - like waterbed Nourishes brain tissue
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Cerebrospinal Fluid Returned to blood at superior sagittal sinus
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Blood-brain barrier Capillaries in the choroid plexus have thicker walls (than capillaries found elsewhere). This means less molecules can passively diffuse into the CSF Most molecules must be actively transported (therefore, they are “selected” to enter) Protects brain from drugs, metabolites, toxins 02 Nov. 2009 CNS1.ppt 13
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Ventricles of the Brain
2 Lateral ventricles (1, 2) in cerebral hemispheres Third ventricle (3) between hemispheres (under the fornix) Cerebral aquaduct connects the 3rd and 4th Fourth ventricle (4) in midbrain and medulla 14
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4 Major Regions of the Brain
Anatomy of the Brain 4 Major Regions of the Brain
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1. Cerebrum or Cerebral Hemisphere
1. Cerebral Hemispheres (Cerebrum) Paired superior parts of the brain Largest part: includes more than half of the brain mass
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The surface is made of ridges (gyri or 1 gyrus) and grooves (sulci or 1 sulcus)
Deeper grooves called fissures exist Longitudinal fissure: separates the right and left hemisphere of the cerebrum
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Cerebrum 4 Lobes of the cerebrum (on each hemisphere)
Lobes are named based on the cranial bones that lie over them Surface lobes of the cerebrum 1. Frontal lobe 2. Parietal lobe 3. Occipital lobe 4. Temporal lobe Central sulcus Lateral sulcus *Parietooccipital sulcus
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Specialized areas of the Cerebrum
Cerebral Cortex: outer layer of the cerebrum (grey matter/cell bodies) Processing of information occurs here Labeled A There are also “islands” of grey matter known as basal nuclei *label B shows white matter/ neural axons- relaying of information occurs here
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Cerebrum Corpus callosum connects the two cerebral hemispheres
It is a nerve tract (bundle of nerves having the same origin and destination) Necessary for communication between the two Labotomy is a procedure that cuts the corpus collasum
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Cerebrum: Cerebral Cortex
(right side controls left side- vice versa) Postcentral gyrus Primary somatic sensory area: receives impulses from the body’s sensory receptors (pain, cold, etc) Precentral gyrus Primary motor area Sends impulses to consciously move skeletal muscles Premotor area Stores sequence activities
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Cerebrum: Cerebral Cortex: Frontal Lobe
Association cortex: involved in planning planning, complex ideas, behaviors, concentratio, ability to focus, emotional traits, judgment and inhibition Broca’s area: Involved in our ability to speak Asymmetric (only on left hemisphere)
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Cerebrum: Cerebral Cortex: Parietal Lobe
Association cortex: receive and utilize information from the lower levels of the brain: temperature, taste, touch, and movement from the rest of the body – such as distance and position of objects
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Cerebrum: Cerebral Cortex: Temporal Lobe
Important for making new memories, and for short-term memory, including memories of taste, sound, sight, and touch Wernicke’s Area responsible for receiving auditory information and recognizing words; it is thus central to the process of learning and understanding language.
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Cerebrum: Cerebral Cortex: Occipital Lobe
primary visual center of the brain, processes information from the eyes, and links that information with images stored in memory. In other words, this area helps you determine what you are looking at.
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Regions of the Brain: 2. Diencephalon
Sits on top of the brain stem Enclosed by the cerebral hemispheres Made of three parts (shown in yellow on brain model) Thalamus Hypothalamus (posterior to optic chiasma) 3. Epithalamus
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Diencephalon Thalamus The relay station for sensory impulses
Transfers impulses to the correct part of the cerebral cortex for localization and interpretation
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Regions of the Brain: Diencephalon
2. Hypothalamus (posterior to optic chiasma) stimulates and controls structures such as the heart, most glands and smooth muscles allows your systems to excite and relax, as needed. Examples: Regulate body temperature Controls water balance Regulates metabolism Drive/emotion, sex, appetite, thirst
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Regions of the Brain: Diencephalon
Hypothalamus The pituitary gland is attached to the hypothalamus
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Diencephalon Epithalamus Location of pineal body
primarily responsible for melatonin cycles Includes the choroid plexus bundle of capillaries that form cerebrospinal fluid
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3. Brain Stem Attaches to the spinal cord Parts of the brain stem
A. Midbrain B. Pons C. Medulla oblongata
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Brain Stem A. Midbrain Tracts of nerve fibers
Reflex centers for vision and hearing Send messages to and from cerebrum Connect the third and fourth ventricles- cerebral aquaduct
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Brain Stem B. Pons The bulging center part of the brain stem
Mostly composed of fiber tracts Controls breathing
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Brain Stem C. Medulla Oblongata The lowest part of the brain stem
Merges into the spinal cord Involuntary control center Heart rate control Blood pressure regulation Breathing/Coughing Swallowing/Gagging Vomiting
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4. Cerebellum Two hemispheres with convoluted surfaces (like the cerebrum) Provides involuntary coordination of body movements (fine motor skills and smooth movements) Balance/Coordination Monitors body position
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