1. Lymphatic system of the brain
Lina Wetzel
Kriti Bhatia

2. Facts
June 1, 2015 published by Dr. Antoine Louveau and Jonathan Kipnis in Nature
Changes in immunity of meninges during stress
T-cells accumulated around dural sinuses in non-blood-containing vessels
Immunohistochemistry
 endothelial specific markers
Also by fluorescent microscopy ( see course of the vessels)

4. Function
meningeal lymphatics are capable of draining fluid from their surrounding environment
Into deep cervical lymph nodes
meningeal lymphatics contain T cells, B cells, and MHC class II-expressing myeloid cells

6. Neurological disease relevance
New therapeutic targets for intervention of neurodegenerative diseases:
Multiple sclerosis
 Replases may be triggered by inflammatory response
Alzheimer’s disease
Amyotrophic lateral sclerosis