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The feasibility of nipple aspiration and duct lavage to evaluate the breast duct epithelium of women with increased breast cancer risk Dominique Twelves, Ashutosh Nerurkar, Peter Osin, Ann Ward, Clare M. Isacke, Gerald P.H. Gui European Journal of Cancer Volume 49, Issue 1, Pages (January 2013) DOI: /j.ejca Copyright © 2012 Elsevier Ltd Terms and Conditions
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Fig. 1 Duct lavage (DL) procedure. Image sequence shows (A) identification of nipple orifice for, (B) insertion of cannula and, (C) saline lavage inflow and aspiration of outflow into syringe. European Journal of Cancer , 65-71DOI: ( /j.ejca ) Copyright © 2012 Elsevier Ltd Terms and Conditions
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Fig. 2 Flowchart of patient recruitment, characteristics of the test cohort and completed visits. European Journal of Cancer , 65-71DOI: ( /j.ejca ) Copyright © 2012 Elsevier Ltd Terms and Conditions
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Fig. 3 Duct lavage (DL) cytology micrographs. Micrographs show samples of duct epithelial cells graded (A) C2 – benign epithelium, (B) C3 – atypical papillary cluster and (C) C4 – marked atypia. Magnification 40×. European Journal of Cancer , 65-71DOI: ( /j.ejca ) Copyright © 2012 Elsevier Ltd Terms and Conditions
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