1. Agarose gel electrophoresis (A,B,C,D) and two-dimensional nondenaturing polyacrylamide gradient gel electrophoresis (E,F) of plasma from a normolipidemic control (A,C,E) and a patient with Tangier disease (B,D,F). Lipoproteins were stained either with fat red (A,B) or anti-apo A-I antibodies (C,D,E,F). In normal plasma, the majority of apo A-I is found in a particle with electrophoretic α-mobility, and a minority in particles with electrophoretic pre-β-mobility (C,E). In Tangier plasma, apo A-I is only found in pre-β1-LpA-I (F). For details of the method see references60 and 67 to 70.
Source: Familial Analphalipoproteinemia: Tangier Disease, The Online Metabolic and Molecular Bases of Inherited Disease
Citation: Valle D, Beaudet AL, Vogelstein B, Kinzler KW, Antonarakis SE, Ballabio A, Gibson K, Mitchell G. The Online Metabolic and Molecular Bases of Inherited Disease; 2014 Available at: Accessed: October 22, 2017
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