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Chapter 71: Vitamin D– Related Disorders

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1 Chapter 71: Vitamin D– Related Disorders
Paul Lips, Natasja M. van Schoor, and Nathalie Bravenboer

2 Table 1. Classification of Vitamin D–Deficient Status
From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition. Table 1. Classification of Vitamin D–Deficient Status © 2008 American Society for Bone and Mineral Research

3 Table 2. Causes of Rickets and Osteomalacia
From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition. Table 2. Causes of Rickets and Osteomalacia © 2008 American Society for Bone and Mineral Research

4 From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition.
Table 3. Recommended Dietary Intake of Vitamin D in Micrograms per Day* © 2008 American Society for Bone and Mineral Research

5 From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition.
Figure 1 Figure 1 The pathway from vitamin D deficiency to falls and fractures. Figure 1 The pathway from vitamin D deficiency to falls and fractures. © 2008 American Society for Bone and Mineral Research

6 From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition.
Figure 2 Figure 2 Osteomalacia in a patient with celiac disease. Goldner stain: mineralized bone is black and osteoid tissue is gray. Besides thick osteoid seams, increased bone resorption by multinucleated osteoclasts (arrows) is visible. Figure 2 Osteomalacia in a patient with celiac disease. Goldner stain: mineralized bone is black and osteoid tissue is gray. Besides thick osteoid seams, increased bone resorption by multinucleated osteoclasts (arrows) is visible. © 2008 American Society for Bone and Mineral Research

7 From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition.
Figure 3 Figure 3 Rickets in a child 1.5 yr of age. (Top) Florid rickets with typical unsharp concave margin of the ulna (arrow). (Bottom) Healing of rickets and appearance of new ossification centers (arrowheads). Figure 3 Rickets in a child 1.5 yr of age. (Top) Florid rickets with typical unsharp concave margin of the ulna (arrow). (Bottom) Healing of rickets and appearance of new ossification centers (arrowheads). © 2008 American Society for Bone and Mineral Research

8 From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition.
Figure 4 Figure 4 Pseudofracture (arrow) in the left os ilium in a patient with osteomalacia. Figure 4 Pseudofracture (arrow) in the left os ilium in a patient with osteomalacia. © 2008 American Society for Bone and Mineral Research


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