1. Volume 6, Issue 1, Pages 127-133 (July 2002)
Increased Vascularity Detected by Digital Subtraction Angiography after VEGF Gene Transfer to Human Lower Limb Artery: A Randomized, Placebo-Controlled, Double- Blinded Phase II Study 
Kimmo Mäkinen, Hannu Manninen, Marja Hedman, Pekka Matsi, Hanna Mussalo, Esko Alhava, Seppo Ylä-Herttuala 
Molecular Therapy 
Volume 6, Issue 1, Pages (July 2002)
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Copyright © 2002 American Society for Gene Therapy Terms and Conditions

2. FIG. 1
Study protocol.
Molecular Therapy 2002 6, DOI: ( /mthe )
Copyright © 2002 American Society for Gene Therapy Terms and Conditions

3. FIG. 2
Representative DSA at 3 months follow-up. (A) Control patient. PTA of anterior tibial artery occlusion. DSA demonstrates continued patency at the angioplasty site (arrow). There was no detectable increase in peripheral vascularity at follow-up. (B) VEGF-Ad patient. Infrapopliteal PTA. Follow-up DSA demonstrates continued patency of the gene-delivery site at proximal anterior tibial artery (arrow) and increased peripheral vascularity in comparison with post-PTA DSA. (C) VEGF-P/L patient. PTA of peroneal artery stenosis. Continued patency at the gene-delivery site (arrow) and increased peripheral vascularity in comparison with post-PTA DSA.
Molecular Therapy 2002 6, DOI: ( /mthe )
Copyright © 2002 American Society for Gene Therapy Terms and Conditions