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Course Content
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Carbohydrates: function and classification:
-monosaccharides structure, epimers, optical activity,solubility, cyclic structure, anomers, reducing sugars, monosaccharide derivatives. -Functions of glucose ,fructose and galactose -Reactions of simple sugars Glycosidic bonds (Types and structure) oligosaccharides:structure of disaccharides(e.g maltose, lactose, sucrose),structure of trisaccharides . polysaccharides: classification, structure and Function. Storage polysaccharides: starch. glycogen Structural Polysaccharides:, cellulose, chitin, .
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● Functional polysaccharides: glycosaminoglycans and heparin.
Gylcoproteins and there functions : adhesion, immunology, recognition Introduction to sugar metabolism Lipids: definition, function, fatty acids, classification: -simple lipids: structure and function (TAG,waxes) -compound lipids: structure and function (phospholipids, sphingolipids) -derived lipids: structure and function (cholesterol, bile acids) Lipoproteins, micelle, membrane structure.
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● Glycerophospholipids (classifications, types& function)
Sphingolipids (classifications, types& function) Triglycerides.Steroids ( structure,properties,&functions ;cholesterol, terpenes, vitamins& steroid hormones ●Lipoproteins ● Introduction to biomembranes and adipocytes Assembly of lipid molecules (membrane and adipose tissue) Fluid mosaic model and types of membrane proteins Fat storage & mobilization in adipose tissue ● Introduction to lipid metabolism ● Nucleic acids: structure of a nucleotide, types of nitrogen bases, structure of nucleosides, nomenclature of nucleosides and nucleotides, phosphodiester bonds, properties of nitrogen bases,
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Vitamins, Hormones, Co-enzymes , Heme and minerals
Roles of functional nucleotides Nucleotides derivatives ( NAD, NADP, FAD, FMN, c AMP, c GMP) Over view of DNA and RNA. DNA primary structure: Description and orientation of bonds RNA : Types, role and structure. Secondary structure of DNA (double helix) Double helix properties, base pairing , reading, stabilizing forces. DNA denaturation : significance and factors Tertiary structure of DNA(relaxed, coiled and associated proteins; histones,protamines. Genetic code, exon and introns: Gene, genome and chromosome. Introduction to replication,transcription and translation and important enzymes. Vitamins, Hormones, Co-enzymes , Heme and minerals
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Reference Harvey . R A and Ferrier .D R. {2011 ) , Lippincott’s Illustrated Reviews: Biochemistry. Lippincott Williams & Wilkins, a Wolters Kluwer business . Philadelphia. Fifth Edition •Lehninger, A.L., Nelson,D.L., Cox,M.M, Principles of Biochemistry,Worth publishers,Inc.,NewYork • Voet,D., Voet,J. , (1995), Biochemistry, John Wiley & Sons,Inc., NewYork • Stryer, L; Biochemistry, W.H. Freeman and company,.,NewYork
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