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Radiation Therapy Overview
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What is Radiation? “energy in motion” waves or streams of particles
Can’t see it or feel it different forms of radiation
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Types of Radiation At one end of the spectrum….. visible light
ultraviolet light radio sound “non-ionizing”
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At the other end….. High Energy “ionizing”
produces ions (charged atoms) eg. photons, protons, electrons, neutrons
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Ionizing Radiation Used in treatment of disease (malignant and benign)
Linear accelerators X-rays Electrons Radioactive isotopes (HDR)
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How does RT work? = Cell Death Damage to Parts of the cell DNA water
proteins cell membrane DNA = Cell Death
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Goal of Radiation Therapy
Maximize dose to tumour & Minimize dose to normal tissue / critical structures
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Radical Treatment (aim to cure)
Combined with: Chemotherapy (before, after, during) Surgery (before, after) Hormones (before, after, during)
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Palliative Treatment Quality of life Relief of symptoms
pain bleeding Obstruction Spinal Cord Compression eg. metastatic cancer to bone, brain, lung
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Radiation Therapy Department
Main floor of TBRHSC (2nd level) Separate reception and waiting area Chemotherapy / medical oncologists are upstairs on 3rd level
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2nd Floor Radiation Therapy Dept.
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Treatment Units Linear Accelerators x 2
Photons (deep seated tumours eg. pelvis) Electrons (superficial eg. skin)
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Entrance to Rx room
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Entrance to treatment machine (Linac 3)
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Linear Accelerator (Siemens ONCOR)
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External Beam RT The process begins…..
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CT-Simulation a.k.a. “Planning Scan”
1 hour appointment May require cast (done 2 hours before CT) Patient education (30 minutes) Consent CT-Simulation (15-30 minutes)
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CT Simulation Treatment position
Important to maintain position / keep still Positioning devices (standard or custom Reference marks placed on patient
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Head & Neck Shell
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Head Shell
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Hip Fix (prostate)
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Positioning Devices Prone pillow Wingboard
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Positioning Devices (cont’d)
Knee rest Foot rest Breast Board
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After CT Scan Patient is finished & can go…… Tattoos / marks
will receive a phone call with next appointment Approximately 1-2 weeks for radical tmt Couple of days or same day for palliative patients
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Preparation for Planning
All further work done on computer Critical structures outlined (by therapist) Spinal cord, rectum, bladder, eyes, kidney, etc. Tumour is outlined (by Rad. Onc)
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Virtual Simulation
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Next step…. Treatment Planning / Dosimetry
Shows the doses of radiation within the treatment area and to critical structures near by May take up to 2 weeks to complete this step Approval by Oncologist
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Radiation Dose Distribution
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Comparison of Process Radical Palliative CT-Simulation 1 hour Planning
Complex (up to 2 weeks) Simple (same or next day) # of treatments 15-40 Mon to Fri 1-10 Emergency (weekends/evenings) Sites Prostate, breast, brain, H & N Metastatic disease (eg. Bone mets)
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1st Day on Treatment Unit
“Dry run” Review treatment with patient Process Side effects Questions
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Day 1 cont’d Electronic images done (like an x-ray) Measurements
Review images Treatment begins!!! Final approval by Oncologist
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While on treatment….. Assessed daily by Radiation Therapists
Weekly assessment by Radiation Oncologist and Nurse (or as necessary) CBC Weeks 1 and 4 As necessary
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Side Effects of RT Localized depends on area being treated
size of area treated Severity depends on dose of radiation Adjuvant treatment (eg. Chemo) Condition of the patient
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General Acute Side Effects
Can occur for any site treated with radiation 1. Skin Reaction (erythema, pruritis, dry & moist desquamation) 2. Fatigue
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Skin Reaction Why? Damages the cells within the basal layer of the skin When? Erythema / dry desquamation – usually 1-2 weeks into Rx Peak may occur at the end of the Rx or about 1 week post Rx Healing will occur 2-4 weeks after RT complete
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Skin Reaction Erythema Dry Desquamation Moist Desquamation
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Skin – Ways to help Keep area clean (gentle washing with mild soap, pat dry) Allow air to get at the area Apply Lubriderm (non-scented, non-greasy) Protect from sun & wind Reduce mechanical irritation (i.e. loose clothing, don’t scratch) No heating pads/ice packs Prescription cream – Hydrocortisone 1%, Flamazine after tmt complete
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Fatigue Why? Cell damage/repair; cachexia; nausea; disease processes; pain; adjuvant Rx; medications May occur 1-2 weeks into Rx May increase after Rx finished, but will resolve with time
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Ways to help…. Rest, nap, sleep Light exercise (brisk walk)
Delegating tasks, setting priorities Dietary counselling Stress management techniques Fatigue booklet & video available
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Other Important Points
Clinical Trials Department – research to improve standards of treatment and patient outcomes Radiation Therapy In-Patient Form - in hospital chart
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Questions?
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