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Disorder-specific functional abnormalities during temporal discounting in youth with Attention Deficit Hyperactivity Disorder (ADHD), Autism and comorbid.

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Presentation on theme: "Disorder-specific functional abnormalities during temporal discounting in youth with Attention Deficit Hyperactivity Disorder (ADHD), Autism and comorbid."— Presentation transcript:

1 Disorder-specific functional abnormalities during temporal discounting in youth with Attention Deficit Hyperactivity Disorder (ADHD), Autism and comorbid ADHD and Autism  Kaylita Chantiluke, Anastasia Christakou, Clodagh M. Murphy, Vincent Giampietro, Eileen M. Daly, Christina Ecker, Michael Brammer, Declan G. Murphy, Katya Rubia  Psychiatry Research: Neuroimaging  Volume 223, Issue 2, Pages (August 2014) DOI: /j.pscychresns Copyright © 2014 The Authors Terms and Conditions

2 Fig. 1 Graph showing the subjective indifference value for the delayed value of £100 for each delay for each group. ADHD=Attention Deficit Hyperactivity Disorder; ASD=Autism Spectrum Disorder; comorbid: group with both ADHD and ASD. The subjective value of £100 decreases as a function of delay, more steeply in ASD and at a trend-level in the comorbid group relative to controls. Psychiatry Research: Neuroimaging  , DOI: ( /j.pscychresns ) Copyright © 2014 The Authors Terms and Conditions

3 Fig. 2 Horizontal slices showing brain regions that correlated with temporal discounting during delayed choices for each group. (A) Healthy controls, (B) ADHD, (C) ASD and (D) Comorbid ADHD and ASD. Talairach z-coordinates are indicated for slice distance (in mm) from the intercommissural line. The right side of the image corresponds to the right side of the brain. Psychiatry Research: Neuroimaging  , DOI: ( /j.pscychresns ) Copyright © 2014 The Authors Terms and Conditions

4 Fig. 3 Conjunction analysis. Axial slices show brain areas that correlated with temporal discounting during delayed choices in any of the 4 groups. Talairach z-coordinates are indicated for slice distance (in mm) from the intercommissural line. The right side of the image corresponds to the right side of the brain. Psychiatry Research: Neuroimaging  , DOI: ( /j.pscychresns ) Copyright © 2014 The Authors Terms and Conditions


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