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Assist Devices for the Treatment of Cardiogenic Shock

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Presentation on theme: "Assist Devices for the Treatment of Cardiogenic Shock"— Presentation transcript:

1 Assist Devices for the Treatment of Cardiogenic Shock
Ezequiel J Molina, MD Attending Cardiac Surgeon Advanced Heart Failure and Transplant Program MedStar Heart and Vascular Institute – Washington Hospital Center Washington, DC I have no relevant financial relationships

2 Background Mortality rate of refractory cardiogenic shock is high
Early initiation of MCS may improve outcomes Avoid progression of MSOF and optimize organ function Potential outcomes: Heart recovery Heart transplantation Temporary or durable LVAD Withdrawal of care and death

3 Ideal Support Device Easy and rapid implementation
Provide robust hemodynamic support Biventricular support when needed Allow pulmonary support Cost effective Multidisciplinary team approach

4 Device Selection Patient status and location
Etiology of cardiogenic shock Technology available at your institution Devices: VA ECMO CentriMag LVAD Durable LVAD

5 VA ECMO

6 VA ECMO Abrams et al, J Am Coll Cardiol, 2014

7 ELSO Survival Data

8 ECMO Outcomes AMI Negi et al, J Invasive Cardiol, 2016

9 ECMO Outcomes AMI Negi et al, J Invasive Cardiol, 2016

10 ECMO Advantages Allows for minimally invasive
Rapid bedside application Biventricular support Pulmonary support Low initial cost Transport capabilities

11 ECMO Advantages

12 ECMO Disadvantages Labor intensive High cost with prolonged support
Requires anticoagulation LV distension / thrombosis Historically high complication rates Limited duration of support

13 LV Distension Inotropes Minimize vasoconstriction Central cannulation
LV vent insertion LVAD conversion Impella / Tandem Heart

14 CentriMag LVAD

15 CentriMag LVAD Magnetically levitated centrifugal blood pump
Low shear stress of blood components LVAD, RVAD or BiVAD Allows ECMO (oxygenator) Flows up to 10 L/min Optimal LV decompression Bridge to recovery, transplant or long term device

16 Disadvantages of CentriMag LVAD
More expensive than ECMO Requires sternotomy Thromboembolic complications Anticoagulation / Bleeding May select patients with no exit strategy

17 CentriMag LVAD Takayama et al, J Heart Lung Transplant, 2013

18 Durable LVADs

19 INTERMACS Profiles

20 Durable LVADs Kirklin et al, J Heart Lung Transplant, 2015

21 LVAD Survival Kirklin et al, J Heart Lung Transplant, 2015

22 LVAD Survival Kirklin et al, J Heart Lung Transplant, 2015

23 Conclusions Early and rapid recognition of cardiogenic shock
Robust hemodynamic support may improve outcomes ECMO is our first line of therapy for cardiopulmonary support… before MSOF CentriMag LVADs as bridge to recovery, transplantation or durable LVADs Durable LVADs can be successful in selected INTERMACS 1 patients Teamwork and communication at each stage is critical Management guidelines are needed but difficult to develop

24 Q&A

25 Tandem Heart

26 Tandem Heart Cheng et al, European Heart Journal, 2009


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