1. SGD- cytoskeleton and cell junctions
Attention - Class of 2016
SGD- cytoskeleton and cell junctions
, 8.00 am
Please read these topics from ‘Human Physiology- From Cells to System’ by Lauralee Sheerwood Latest Edition
You may also consult ‘Textbook of Medical Physiology’ by Guyton & Hall Latest Edition.
Focus on:
1. In Cytoskeleton
Role of microtubules in maintenance of cell shape and complex cell movements
Role of microfilaments in cellular contractile systems and as mechanical stiffeners
Role of intermediate filaments in mechanical stress
How the cytoskeleton links together parts of the cell
2. In Cell to Cell adhesions
Role of extracellular matrix in cell adhesion
Specialized cell junctions: Desmosomes, Tight junctions, Gap Junctions

2. LGD- Structure and varieties of epithelia
Attention - Class of 2016
LGD- Structure and varieties of epithelia
, 8.00 am
You should know the following facts of epithelium:
General features of epithelial tissue
Functions of epithelium
Classification of epithelia
Morphology, location and functions of various types of covering/lining epithelia
Features and location of specialized types of epithelia
Modifications of apical domain of epithelial cells
Composition and functions of basal lamina and basement membrane
Classification of glands and their location
Different modes of glandular secretion
Features of serous, mucous and myoepithelial cells

3. Attention - Class of 2016 SGD- DNA replication 14-12-11, 8.00 am
Consult “Lippincott’s Illustrated Reviews”
5th Edition
Chapter 29, pages
Focus on:
the process of DNA replication (the enzymes involved and the activities taking place at the replication forks)
the role of telomeres in aging and cancer
Please refer to the study guide pages for further guidance
(You must be familiar with the structure of DNA to understand DNA replication)

4. Attention - Class of 2016
SGD- Gene transcription in Prokaryotes and Eukaryotes
, 1.30 pm
Consult “Lippincott’s Illustrated Reviews”
Fifth Edition
Chapter 30 pages
Focus on:
the major types of cellular RNA and their functions
the major steps of gene transcription (initiation, elongation and termination) in prokaryotes and eukaryotes
the major differences between prokaryotic and eukaryotic gene transcription
Please refer to the study guide pages 25 for further guidance

5. SGD- Protein synthesis Consult “Lippincott’s Illustrated Reviews”
Attention - Class of 2016
SGD- Protein synthesis
, 1.30 pm
Consult “Lippincott’s Illustrated Reviews”
Fifth Edition
Chapter 31, pages
Focus on:
how the nucleotide sequence is translated into the amino acid sequence of a protein
the components required for protein synthesis
initiation, elongation and termination of protein synthesis
how differences in prokaryotic and eukaryotic protein synthesis have been exploited to produce various antibiotics
Post-translational modification of proteins

6. Attention - Class of 2016
SGD- Regulation of gene expression in eukaryotes
, am
Consult “Lippincott’s Illustrated Reviews”
Fifth Edition
Chapter 32, pages
Focus on regulation of eukaryotic gene expression through:
trans- and cis- acting molecules
intracellular and cell surface receptors
alternative splicing
mRNA editing
mRNA stability in iron metabolism (we’ll do RNA interference in therapeutics)
translation of mRNA
modifications to DNA