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Copyright © 2003 American Medical Association. All rights reserved.

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Presentation on theme: "Copyright © 2003 American Medical Association. All rights reserved."— Presentation transcript:

1 Copyright © 2003 American Medical Association. All rights reserved.
From: Renin-Angiotensin System and Atherothrombotic DiseaseFrom Genes to Treatment Arch Intern Med. 2003;163(10): doi: /archinte Figure Legend: Mechanisms by which angiotensin II promotes atherosclerosis. Most effects result from signaling through the angiotensin II type 1 receptor. IL-6 indicates interleukin 6; MCP-1, monocyte chemoattractant protein-1; PDGF, platelet-derived growth factor; LOX-1, lectin-like oxidized low-density lipoprotein receptor; VCAM, vascular cellular adhesion molecule; ICAM, intracellular adhesion molecule; TGF-β, transforming growth factor β; PAI-1, plasminogen activator inhibitor-1; TF, tissue factor; and NO, nitric oxide. Date of download: 10/23/2017 Copyright © 2003 American Medical Association. All rights reserved.

2 Copyright © 2003 American Medical Association. All rights reserved.
From: Renin-Angiotensin System and Atherothrombotic DiseaseFrom Genes to Treatment Arch Intern Med. 2003;163(10): doi: /archinte Figure Legend: Key members of the renin-angiotensin system cascade. Date of download: 10/23/2017 Copyright © 2003 American Medical Association. All rights reserved.


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