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A section of the cerebellum stained with Sevier-Munger preparation from the brain of a 10-year-old SCA1 patient with 82 CAG repeats who died after 6 years.

Published byToby Lambert Modified over 6 years ago

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Presentation on theme: "A section of the cerebellum stained with Sevier-Munger preparation from the brain of a 10-year-old SCA1 patient with 82 CAG repeats who died after 6 years."— Presentation transcript:

1 A section of the cerebellum stained with Sevier-Munger preparation from the brain of a 10-year-old SCA1 patient with 82 CAG repeats who died after 6 years of symptoms. Three Purkinje cells are in a state of degeneration with their axons showing torpedoes in the internal granule cell layer. (Courtesy of Dr. Dawna Armstrong.) Source: Spinocerebellar Ataxias, The Online Metabolic and Molecular Bases of Inherited Disease Citation: Valle D, Beaudet AL, Vogelstein B, Kinzler KW, Antonarakis SE, Ballabio A, Gibson K, Mitchell G. The Online Metabolic and Molecular Bases of Inherited Disease; 2014 Available at: Accessed: October 23, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved

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