1. Connective Tissue Types Cartilage
Dr. Jack L. Haar
Department of Anatomy
Sanger Hall 9-064

2. Cartilage General considerations
Light, flexible, much intercellular substance
Forms quickly
Nutrients supplied by diffusion, no blood vessels

3. B. Embryology Forms very early in development

4. Histological components
Cells
Chondroblasts
Come from mesenchymal cells or multipotential C.T. cells
Differentiate to produce cartilage matrix

5. Chondrocyte (mature cartilage cell) Located in lacunae Golgi, rER , fat droplet possible

6. Intercellular matrix Fiber type depends on type of cartilage Ground substance, mainly chondroitin sulfate Territorial and interterritorial matrix

7. Perichondrium Fibrous layer of dense C.T.
Chondrogenic layer of chondroblasts

8. Perichondrium (cartilage is non-vascular)

9. Growth of cartilage
Appositional
Interstitial

10. Types of cartilage. Hyaline Cartilage – type II collagen
Types of cartilage Hyaline Cartilage – type II collagen Distribution: nose larynx, strachea, bronchi

11. Elastic Cartilage Abundant elastic fiber Branching network
Limited ground substance

12. Distribution
External ear, epiglottis, part of the larynx

13. Fibrocartilage
“Never occurs alone but blends insensibly with neighboring hyaline cartilage, fibrous tissue or bone”
Fiber component
Bundles of collagen type I fibers fill matrix
Chondrocytes
May appear in parallel rows or randomly distributed
Occur in lacunae
Minimal ground substance
Function: strength and transition

14. Function:. Provides stiffness and great tensile strength at tendon
Function: Provides stiffness and great tensile strength at tendon insertions

15. Function:. A transition form from dense FECT and cartilage, provides
Function: A transition form from dense FECT and cartilage, provides shock absorption

17. Distribution Intervertebral disc Annulus fibrosus Nucleus pulposus

18. Distribution Pubic symphysis Tendons to bones

19. Regressive changes in cartilage. a
Regressive changes in cartilage a. Chondrocytes greatly hypertrophy, produce alkaline phosphatase, a calcifiable matrix; b. Calcium phosphate is deposited in matrix; does not allow diffusion of nutrients c. Chondrocytes die leaving behind the calcified matrix

20. Occurrence. a. In some cartilage as it ages. b
Occurrence a. In some cartilage as it ages b. As early stage of bone production

21. http://www. path. uiowa. edu/virtualslidebox/ Table of Contents
Table of Contents Supporting tissue and muscle Hyaline cartilage #5 Elastic cartilage #7