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Schistosomiasis Schistosoma haematobium Schistosoma mansoni

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Presentation on theme: "Schistosomiasis Schistosoma haematobium Schistosoma mansoni"— Presentation transcript:

1 Schistosomiasis Schistosoma haematobium Schistosoma mansoni
Schistosoma japonicum

2 A Brief History... First described by German pathologist
Theodore Maximilian Bilharz Bilharz performed autopsies on Egyptian patients who had died from the disease: found male & female parasite eggs in the liver portal system, bladder. Later seen in Japan, called Katayama fever Symptoms: rash on legs, fever, diarrhoea, bloody stools  emaciation, edema  death.

3 Schistosoma General character: Morphology Reproduction system
Importance

4 Morphology Size: - Female 12 to 26 mm
The three main species infecting humans are Schistosoma haematobium, S. japonicum , and S. mansoni.  Two other species, more localized geographically, are S. mekongi and S. intercalatum

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6 Adult an larve of Sch. Schistosomulum

7 Geographic Distribution
Schistosoma mansoni is found in parts of South America and the Caribbean, Africa, and the Middle East; S. haematobium in Africa and the Middle East; and S. japonicum in the Far East. Schistosoma mekongi and S. intercalatum are found focally in Southeast Asia and central West Africa, respectively.

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9 Life Cycle

10 Schistosoma spp.: miracidium

11 Schistosoma spp. cercariae are the infective forms
Schistosoma spp. cercariae are the infective forms. After encountering the skin, the cercariae penetrate and lose the tail transforming into schistosomulae

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13 S. haematobium Biomphalaria

14 S. mansoni Oncomelania

15 Miracidium & Cercaria

16 Liver worm

17 Schistosoma egg JK Sch.mansoni egg Sch. japonicum egg Sch. Haematobium
                                                          JK Sch.mansoni egg Sch. japonicum egg Sch. Haematobium egg

18 Epidemiology of Schistomiasis

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21 Cercarial Dermatitis

22 Hepatomegaly & splenomegaly

23 Granuloma ( Sch. japonicum egg)

24 Granuloma ( Sch. hematobium egg)

25 Granuloma

26 Laboratory Diagnosis Microscopic identification of eggs in stool or urine is the most practical method for diagnosis. Stool examination should be performed when infection with S. mansoni or S. japonicum is suspected, and urine examination should be performed if S. haematobium is suspected. Tissue biopsy (rectal biopsy for all species and biopsy of the bladder for S. haematobium) may demonstrate eggs when stool or urine examinations are negative.

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